Chang-Zhong Li1, Bo Liu, Ze-Qing Wen, Qiang Sun. 1. Department of Obstetrics and Gynecology, Shandong Provincial Hospital, Shandong University, Jinan, People's Republic of China. lichangzhong@hotmail.com
Abstract
OBJECTIVE: To investigate the impact of electrocoagulation on ovarian reserveafter laparoscopic excision of ovarian cysts and the possible mechanisms. DESIGN: A prospective study. SETTING: Obstetrics and Gynecology Department of a university hospital. PATIENT(S): 191 patients with benign ovarian cysts undergoing ovarian cystectomy. INTERVENTION(S): Laparoscopic ovarian cystectomy using bipolar or ultrasonic scalpel electrocoagulation and laparotomic ovarian cystectomy using sutures after the excision of ovarian cysts. MAIN OUTCOME MEASURE(S): Follicle-stimulating hormone (FSH) assay and transvaginal ultrasound evaluating basal antral follicle number, mean ovarian diameter, and ovarian stromal blood flow velocity at day 3 of menstrual cycles 1, 3, 6, and 12 after surgery. RESULT(S): When comparing the bipolar group and ultrasonic scalpel group with the suture group, a statistically significant increase of the mean FSH value was found in bilateral-cyst patients at 1-, 3-, 6-, and 12-month follow-up evaluations and in unilateral-cyst patients at the 1-month follow-up evaluation. Statistically significant decreases of basal antral follicle number and mean ovarian diameter were found during the 3-, 6-, 12-month follow-up evaluations as well as statistically significant decreases of peak systolic velocity at all of the follow-up evaluations. CONCLUSION(S): Electrocoagulationafter laparoscopic excision of ovarian cysts is associated with a statistically significant reduction in ovarian reserve, which is partly a consequence of the damage to the ovarian vascular system.
RCT Entities:
OBJECTIVE: To investigate the impact of electrocoagulation on ovarian reserve after laparoscopic excision of ovarian cysts and the possible mechanisms. DESIGN: A prospective study. SETTING: Obstetrics and Gynecology Department of a university hospital. PATIENT(S): 191 patients with benign ovarian cysts undergoing ovarian cystectomy. INTERVENTION(S): Laparoscopic ovarian cystectomy using bipolar or ultrasonic scalpel electrocoagulation and laparotomic ovarian cystectomy using sutures after the excision of ovarian cysts. MAIN OUTCOME MEASURE(S): Follicle-stimulating hormone (FSH) assay and transvaginal ultrasound evaluating basal antral follicle number, mean ovarian diameter, and ovarian stromal blood flow velocity at day 3 of menstrual cycles 1, 3, 6, and 12 after surgery. RESULT(S): When comparing the bipolar group and ultrasonic scalpel group with the suture group, a statistically significant increase of the mean FSH value was found in bilateral-cyst patients at 1-, 3-, 6-, and 12-month follow-up evaluations and in unilateral-cyst patients at the 1-month follow-up evaluation. Statistically significant decreases of basal antral follicle number and mean ovarian diameter were found during the 3-, 6-, 12-month follow-up evaluations as well as statistically significant decreases of peak systolic velocity at all of the follow-up evaluations. CONCLUSION(S): Electrocoagulation after laparoscopic excision of ovarian cysts is associated with a statistically significant reduction in ovarian reserve, which is partly a consequence of the damage to the ovarian vascular system.
Authors: Márcia M Carneiro; Ivete de Ávila; Patrícia S Gouvea; Maria das Graças M Torres; Ivone D S Filogônio Journal: JBRA Assist Reprod Date: 2014-03-27