Literature DB >> 18930125

Integrating genomics across drug discovery and development.

Christine Debouck1.   

Abstract

The sequencing of the human genome was an exceptional achievement, but it was not an end in itself as it set the foundation for building new knowledge in biology and medicine. The laborious, multifaceted science of drug discovery and development also draws tremendous benefits from mining the human genome and exploiting the large palette of genomic technologies. This article discusses how diverse genomic tools have been used to date and how they will continue to be utilized in the future to impact drug discovery and development. Integrating genomics across drug discovery and development will undoubtedly help to shorten timelines, increase success rates at all stages and ultimately bring the right drugs to the right patients at the right times.

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Year:  2008        PMID: 18930125     DOI: 10.1016/j.toxlet.2008.09.011

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN: 0378-4274            Impact factor:   4.372


  3 in total

1.  Impact of cytokine and cytokine receptor gene polymorphisms on cellular immunity after smallpox vaccination.

Authors:  Inna G Ovsyannikova; Iana H Haralambieva; Richard B Kennedy; V Shane Pankratz; Robert A Vierkant; Robert M Jacobson; Gregory A Poland
Journal:  Gene       Date:  2012-08-23       Impact factor: 3.688

Review 2.  Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery.

Authors:  Nicholas Ekow Thomford; Dimakatso Alice Senthebane; Arielle Rowe; Daniella Munro; Palesa Seele; Alfred Maroyi; Kevin Dzobo
Journal:  Int J Mol Sci       Date:  2018-05-25       Impact factor: 5.923

3.  Planning for translational research in genomics.

Authors:  Naomi Hawkins; Jantina de Vries; Paula Boddington; Jane Kaye; Catherine Heeney
Journal:  Genome Med       Date:  2009-09-29       Impact factor: 11.117

  3 in total

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