| Literature DB >> 18927538 |
Antonella Di Cesare1, Paola Di Meglio2, Frank O Nestle3.
Abstract
Atopic dermatitis (AD) is a common inflammatory skin disease. Both epidermal barrier dysfunction and immunodysregulation are suggested to influence the pathogenesis of AD. AD has been considered a paradigmatic T helper cell (Th) 2-mediated disease, with a switch to a Th1 cell environment during the chronic phase of the disease. Previously unreported findings now suggest a possible role for Th17 cells as well.Entities:
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Year: 2008 PMID: 18927538 DOI: 10.1038/jid.2008.283
Source DB: PubMed Journal: J Invest Dermatol ISSN: 0022-202X Impact factor: 8.551