| Literature DB >> 18926699 |
Junfa Fan1, Bruce Fahr, David Stockett, Erica Chan, Sravanthi Cheeti, Iana Serafimova, Yafan Lu, Phuongly Pham, Duncan H Walker, Ute Hoch, Ingrid C Choong.
Abstract
Modifications of the isonipecotic acid fragment of SNS-032 results in analogs which are more permeable and lower effluxed than SNS-032. The enantiomerically pure synthesis and the in vivo profile of analog 20 is described.Entities:
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Year: 2008 PMID： 18926699 DOI： 10.1016/j.bmcl.2008.09.099
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823