Literature DB >> 18925485

Cognitive and behavioural impairment in Parkinson's disease.

Doron Merims1, Morris Freedman.   

Abstract

Although Parkinson's disease (PD) has been considered to primarily affect motor abilities, increasing emphasis is being placed on cognitive and behavioural impairment in this disorder. Depression, dementia, psychosis and impulse control disorders have a major impact on quality of life for both patients and families. This article reviews cognitive and behavioural disturbances in PD and their relation to affective and motor symptoms, treatment of dementia associated with PD, and treatment approaches to psychosis in PD. We also discuss similarities between the dementia of PD and dementia with Lewy bodies.

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Year:  2008        PMID: 18925485     DOI: 10.1080/09540260802095123

Source DB:  PubMed          Journal:  Int Rev Psychiatry        ISSN: 0954-0261


  5 in total

Review 1.  Profile of cognitive impairment in Parkinson's disease.

Authors:  G Stennis Watson; James B Leverenz
Journal:  Brain Pathol       Date:  2010-05       Impact factor: 6.508

2.  The dopamine and cAMP regulated phosphoprotein, 32 kDa (DARPP-32) signaling pathway: a novel therapeutic target in traumatic brain injury.

Authors:  James W Bales; Hong Q Yan; Xiecheng Ma; Youming Li; Ranmal Samarasinghe; C Edward Dixon
Journal:  Exp Neurol       Date:  2011-03-01       Impact factor: 5.330

3.  The risky business of dopamine agonists in Parkinson disease and impulse control disorders.

Authors:  Daniel O Claassen; Wery P M van den Wildenberg; K Richard Ridderinkhof; Charles K Jessup; Madaline B Harrison; G Frederick Wooten; Scott A Wylie
Journal:  Behav Neurosci       Date:  2011-08       Impact factor: 1.912

Review 4.  Staging neurodegenerative disorders: structural, regional, biomarker, and functional progressions.

Authors:  Trevor Archer; Richard M Kostrzewa; Richard J Beninger; Tomas Palomo
Journal:  Neurotox Res       Date:  2011-02       Impact factor: 3.911

5.  Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance.

Authors:  Charles R Arthur; Stephanie L Morton; Lisa D Dunham; Paula M Keeney; James P Bennett
Journal:  Mol Neurodegener       Date:  2009-09-23       Impact factor: 14.195

  5 in total

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