Literature DB >> 18923510

A glimmer of light for neuropsychiatric disorders.

Steven E Hyman1.   

Abstract

Understanding the pathogenesis of neuropsychiatric disorders is a substantial challenge for neurobiologists. It has long been hoped that identifying alleles that confer increased risk of such disorders would provide clues for neurobiological investigation. But this quest has been stymied by a lack of validated biological markers for characterizing and distinguishing the different disorders and by the genetic complexity underpinning these diseases. Now, modern genomic technologies have begun to facilitate the discovery of relevant genes.

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Year:  2008        PMID: 18923510     DOI: 10.1038/nature07454

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  39 in total

Review 1.  Animal models of neuropsychiatric disorders.

Authors:  Eric J Nestler; Steven E Hyman
Journal:  Nat Neurosci       Date:  2010-09-27       Impact factor: 24.884

2.  How adversity gets under the skin.

Authors:  Steven E Hyman
Journal:  Nat Neurosci       Date:  2009-03       Impact factor: 24.884

3.  Induced pluripotent stem (iPS) cells and their future in psychiatry.

Authors:  Kwang-Soo Kim
Journal:  Neuropsychopharmacology       Date:  2010-01       Impact factor: 7.853

4.  Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses.

Authors:  Sarah R Gilman; Ivan Iossifov; Dan Levy; Michael Ronemus; Michael Wigler; Dennis Vitkup
Journal:  Neuron       Date:  2011-06-09       Impact factor: 17.173

5.  Disruption of Ninjurin1 Leads to Repetitive and Anxiety-Like Behaviors in Mice.

Authors:  Hoang Le; Bum Ju Ahn; Hye Shin Lee; Anna Shin; Sujin Chae; Sung Yi Lee; Min Wook Shin; Eun-Ji Lee; Jong-Ho Cha; Taekwon Son; Ji Hae Seo; Hee-Jun Wee; Hyo-Jong Lee; Yongwoo Jang; Eng H Lo; Sejin Jeon; Goo Taeg Oh; Daesoo Kim; Kyu-Won Kim
Journal:  Mol Neurobiol       Date:  2016-11-05       Impact factor: 5.590

6.  Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

Authors:  Li Fan; Yichao Lu; Xiulian Shen; Hong Shao; Lun Suo; Qiang Wu
Journal:  Elife       Date:  2018-06-18       Impact factor: 8.140

7.  Preconscious processing biases predict emotional reactivity to stress.

Authors:  Elaine Fox; Shanna Cahill; Konstantina Zougkou
Journal:  Biol Psychiatry       Date:  2010-02-15       Impact factor: 13.382

8.  Fetal programming of brain development: intrauterine stress and susceptibility to psychopathology.

Authors:  Claudia Buss; Sonja Entringer; Pathik D Wadhwa
Journal:  Sci Signal       Date:  2012-10-09       Impact factor: 8.192

9.  Physiologically based pharmacokinetic modelling to predict single- and multiple-dose human pharmacokinetics of bitopertin.

Authors:  Neil Parrott; Dominik Hainzl; Daniela Alberati; Carsten Hofmann; Richard Robson; Bruno Boutouyrie; Meret Martin-Facklam
Journal:  Clin Pharmacokinet       Date:  2013-08       Impact factor: 6.447

10.  GABA and homovanillic acid in the plasma of Schizophrenic and bipolar I patients.

Authors:  Aurora Arrúe; Ricardo Dávila; Mercedes Zumárraga; Nieves Basterreche; Miguel A González-Torres; Biotza Goienetxea; Maria I Zamalloa; Juan B Anguiano; José Guimón
Journal:  Neurochem Res       Date:  2009-08-22       Impact factor: 3.996

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