Literature DB >> 18923086

Seizures are common in the acute setting of childhood stroke: a population-based study.

Madeline A Chadehumbe1, Pooja Khatri, Jane C Khoury, Kathleen Alwell, Jerzy P Szaflarski, Joseph P Broderick, Brett M Kissela, Dawn O Kleindorfer.   

Abstract

In our large population-based cohort, 3.1% of adults had seizures within the first 24 h of acute stroke. The objective of our study was to determine a similar incidence in children and compare by stroke subtype. Stroke cases in children between July 1993 to June 1994 and January 1999 to December 1999 were retrospectively identified and abstracted. We identified 31 strokes during the two study periods, including 17 ischemic strokes, 12 intracerebral hemorrhages, and 2 subarachnoid hemorrhages. Seizures occurred within 24 h of the stroke in 58% (18/31) of children. No significant differences were found in the rate of seizure by stroke subtype. The relative risk (95% confidence interval) for seizure in the acute stroke setting in children versus adults is 18 (13, 26). As compared with adults, seizures within the acute setting of childhood stroke are common with an occurrence rate in our population of 58%.

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Year:  2008        PMID: 18923086      PMCID: PMC2896819          DOI: 10.1177/0883073808320756

Source DB:  PubMed          Journal:  J Child Neurol        ISSN: 0883-0738            Impact factor:   1.987


  30 in total

1.  Epilepsy in cerebral vascular disease; a study of the incidence and nature of seizures in 104 consecutive autopsy-proven cases of cerebral infarction and hemorrhage.

Authors:  E P RICHARDSON; P R DODGE
Journal:  Epilepsia       Date:  1954-11       Impact factor: 5.864

2.  Prevalence and predictors of early seizure and status epilepticus after first stroke.

Authors:  D L Labovitz; W A Hauser; R L Sacco
Journal:  Neurology       Date:  2001-07-24       Impact factor: 9.910

3.  Childhood ischemic stroke in a nonurban population.

Authors:  Michael D Bowen; Christopher R Burak; Todd F Barron
Journal:  J Child Neurol       Date:  2005-03       Impact factor: 1.987

4.  Temporal trends in the incidence and case fatality of stroke in children and adolescents.

Authors:  Dawn Kleindorfer; Jane Khoury; Brett Kissela; Kathy Alwell; Daniel Woo; Rosemary Miller; Alexander Schneider; Charles Moomaw; Joseph P Broderick
Journal:  J Child Neurol       Date:  2006-05       Impact factor: 1.987

5.  Accuracy and yield of ICD-9 codes for identifying children with ischemic stroke.

Authors:  Meredith R Golomb; Bhuwan P Garg; Chandan Saha; Linda S Williams
Journal:  Neurology       Date:  2006-12-12       Impact factor: 9.910

6.  Age-related variation in presenting signs of childhood arterial ischemic stroke.

Authors:  Jennifer A Zimmer; Bhuwan P Garg; Linda S Williams; Meredith R Golomb
Journal:  Pediatr Neurol       Date:  2007-09       Impact factor: 3.372

7.  Incidence of seizures in the acute phase of stroke: a population-based study.

Authors:  Jerzy P Szaflarski; Angela Y Rackley; Dawn O Kleindorfer; Jane Khoury; Daniel Woo; Rosemary Miller; Kathleen Alwell; Joseph P Broderick; Brett M Kissela
Journal:  Epilepsia       Date:  2008-01-31       Impact factor: 5.864

8.  Seizures associated with stroke in childhood.

Authors:  J S Yang; Y D Park; P L Hartlage
Journal:  Pediatr Neurol       Date:  1995-02       Impact factor: 3.372

9.  Population-based study of seizure disorders after cerebral infarction.

Authors:  E L So; J F Annegers; W A Hauser; P C O'Brien; J P Whisnant
Journal:  Neurology       Date:  1996-02       Impact factor: 9.910

10.  Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989.

Authors:  R D Brown; J P Whisnant; J D Sicks; W M O'Fallon; D O Wiebers
Journal:  Stroke       Date:  1996-03       Impact factor: 7.914

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  15 in total

1.  Seizures as a presenting symptom of acute arterial ischemic stroke in childhood.

Authors:  Nicholas S Abend; Lauren A Beslow; Sabrina E Smith; Sudha K Kessler; Arastoo Vossough; Stefanie Mason; Shannon Agner; Daniel J Licht; Rebecca N Ichord
Journal:  J Pediatr       Date:  2011-03-22       Impact factor: 4.406

2.  Potential eligibility for recombinant tissue plasminogen activator therapy in children: a population-based study.

Authors:  Laura L Lehman; Dawn O Kleindorfer; Jane C Khoury; Kathleen Alwell; Charles J Moomaw; Brett M Kissela; Pooja Khatri
Journal:  J Child Neurol       Date:  2011-05-31       Impact factor: 1.987

Review 3.  Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium.

Authors:  Adriane J Sinclair; Christine K Fox; Rebecca N Ichord; Christopher S Almond; Timothy J Bernard; Lauren A Beslow; Anthony K C Chan; Michael Cheung; Gabrielle deVeber; Michael M Dowling; Neil Friedman; Therese M Giglia; Kristin P Guilliams; Tilman Humpl; Daniel J Licht; Mark T Mackay; Lori C Jordan
Journal:  Pediatr Neurol       Date:  2014-10-05       Impact factor: 3.372

Review 4.  Childhood stroke.

Authors:  Peter B Sporns; Heather J Fullerton; Sarah Lee; Helen Kim; Warren D Lo; Mark T Mackay; Moritz Wildgruber
Journal:  Nat Rev Dis Primers       Date:  2022-02-24       Impact factor: 52.329

5.  Thrombin facilitates seizures through activation of persistent sodium current.

Authors:  Elena Isaeva; Amanda Hernan; Dmytro Isaev; Gregory L Holmes
Journal:  Ann Neurol       Date:  2012-08       Impact factor: 10.422

6.  Pediatric intracerebral hemorrhage: acute symptomatic seizures and epilepsy.

Authors:  Lauren A Beslow; Nicholas S Abend; Melissa C Gindville; Rachel A Bastian; Daniel J Licht; Sabrina E Smith; Argye E Hillis; Rebecca N Ichord; Lori C Jordan
Journal:  JAMA Neurol       Date:  2013-04       Impact factor: 18.302

Review 7.  Mechanisms of perinatal arterial ischemic stroke.

Authors:  David Fernández-López; Niranjana Natarajan; Stephen Ashwal; Zinaida S Vexler
Journal:  J Cereb Blood Flow Metab       Date:  2014-03-26       Impact factor: 6.200

8.  Pediatric stroke presenting as a seizure.

Authors:  Katie L Ahmadzadeh; Vartika Bhardwaj; Steven A Johnson; Kathleen E Kane
Journal:  Case Rep Emerg Med       Date:  2014-12-22

9.  Differentiating Childhood Stroke From Mimics in the Emergency Department.

Authors:  Mark T Mackay; Adriana Yock-Corrales; Leonid Churilov; Paul Monagle; Geoffrey A Donnan; Franz E Babl
Journal:  Stroke       Date:  2016-09-06       Impact factor: 7.914

10.  Neurological outcome after arterial ischemic stroke in children.

Authors:  Jafar Nasiri; Alireza Ariyana; Omid Yaghini; Mohammad Reza Ghazavi; Mojtaba Keikhah; Mehri Salari
Journal:  Adv Biomed Res       Date:  2016-06-08
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