Literature DB >> 18922882

Treatment of the elderly colorectal cancer patient: SIOG expert recommendations.

D Papamichael1, R Audisio, J-C Horiot, B Glimelius, J Sastre, E Mitry, E Van Cutsem, M Gosney, C-H Köhne, M Aapro.   

Abstract

Colorectal cancer (CRC) is one of the commonest malignancies of Western countries, with approximately half the incidence occurring in patients >70 years of age. Elderly CRC patients, however, are understaged, undertreated and underrepresented in clinical trials. The International Society of Geriatric Oncology created a task force with a view to assessing the potential for developing guidelines for the treatment of elderly (geriatric) CRC patients. A review of the evidence presented by the task force members confirmed the paucity of clinical trial data in elderly people and the lack of evidence-based guidelines. However, recommendations have been proposed on the basis of the available data and on the emerging evidence that treatment outcomes for fit, elderly CRC patients can be similar to those of younger patients. It is hoped that these will pave the way for formal treatment guidelines based upon solid scientific evidence in the future.

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Year:  2008        PMID: 18922882     DOI: 10.1093/annonc/mdn532

Source DB:  PubMed          Journal:  Ann Oncol        ISSN: 0923-7534            Impact factor:   32.976


  50 in total

1.  Effects of newly developed chemotherapy regimens, comorbidities, chemotherapy-related toxicities on the changing patterns of the leading causes of death in elderly patients with colorectal cancer.

Authors:  L Tong; C Ahn; E Symanski; D Lai; X L Du
Journal:  Ann Oncol       Date:  2014-03-27       Impact factor: 32.976

2.  Laparoscopic assisted insertion of a colonic self-expandable metallic stent.

Authors:  Y M Ho; V Shenoy; J Alberts; N Ward
Journal:  Tech Coloproctol       Date:  2018-11-17       Impact factor: 3.781

Review 3.  Locally Advanced Rectal Cancer: Treatment Approach in Elderly Patients.

Authors:  Francesca De Felice; Daniele Crocetti; Veronica Maiuri; Martina Parisi; Francesco Marampon; Luciano Izzo; Giorgio De Toma; Daniela Musio; Vincenzo Tombolini
Journal:  Curr Treat Options Oncol       Date:  2020-01-11

Review 4.  Treatment of colorectal cancer in the elderly.

Authors:  Monica Millan; Sandra Merino; Aleidis Caro; Francesc Feliu; Jordi Escuder; Tani Francesch
Journal:  World J Gastrointest Oncol       Date:  2015-10-15

5.  Increasing age-related survival gap among patients with colorectal cancer: a population-based retrospective study.

Authors:  Yang Feng; Shaobo Mo; Weixing Dai; Qingguo Li; Guoxiang Cai; Sanjun Cai
Journal:  Int J Clin Oncol       Date:  2019-09-17       Impact factor: 3.402

6.  The effect of marital status by age on patients with colorectal cancer over the past decades: a SEER-based analysis.

Authors:  Yang Feng; Weixing Dai; Yaqi Li; Shaobo Mo; Qingguo Li; Sanjun Cai
Journal:  Int J Colorectal Dis       Date:  2018-03-15       Impact factor: 2.571

Review 7.  Factors influencing adherence to cancer treatment in older adults with cancer: a systematic review.

Authors:  M T E Puts; H A Tu; A Tourangeau; D Howell; M Fitch; E Springall; S M H Alibhai
Journal:  Ann Oncol       Date:  2013-11-26       Impact factor: 32.976

8.  Primary colonic signet ring cell carcinoma in a young patient.

Authors:  Raghunath Prabhu; Neha Kumar; Sunil Krishna; Rajgopal Shenoy
Journal:  BMJ Case Rep       Date:  2014-03-20

Review 9.  Colon cancer and the elderly: from screening to treatment in management of GI disease in the elderly.

Authors:  Peter R Holt; Peter Kozuch; Seetal Mewar
Journal:  Best Pract Res Clin Gastroenterol       Date:  2009       Impact factor: 3.043

Review 10.  Treatment of colorectal cancer in older patients.

Authors:  Riccardo A Audisio; Demetris Papamichael
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2012-10-09       Impact factor: 46.802

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