OBJECTIVE: This study compared physiological differences between children diagnosed with migraine and their healthy peers. METHOD: Physiological measures were obtained at baseline, after discussing an emotional stressor, and after a 5-min recovery period in 21 children with pediatric migraine and 32 healthy peers. Comparisons were also made on psychological measures investigating anxiety. RESULTS: Children with migraine exhibited a significantly higher pulse rate compared to comparison children at rest, and higher diastolic blood pressure and higher low-frequency/high-frequency ratio after a 5-min recovery from an emotional stressor. Additionally, when anxiety was entered as a covariate, group differences after the 5-min recovery period were no longer significant. CONCLUSIONS: Results suggest that relative to comparison children, children with migraine exhibit some physiological elevation at rest, as well as a prolonged physiological recovery period after an emotional stressor. Group differences after the 5-min recovery period suggest that children with migraine experience delayed sympathetic hyperarousal and prolonged sympathovagal imbalance. The treatment implications of these findings are discussed.
OBJECTIVE: This study compared physiological differences between children diagnosed with migraine and their healthy peers. METHOD: Physiological measures were obtained at baseline, after discussing an emotional stressor, and after a 5-min recovery period in 21 children with pediatric migraine and 32 healthy peers. Comparisons were also made on psychological measures investigating anxiety. RESULTS:Children with migraine exhibited a significantly higher pulse rate compared to comparison children at rest, and higher diastolic blood pressure and higher low-frequency/high-frequency ratio after a 5-min recovery from an emotional stressor. Additionally, when anxiety was entered as a covariate, group differences after the 5-min recovery period were no longer significant. CONCLUSIONS: Results suggest that relative to comparison children, children with migraine exhibit some physiological elevation at rest, as well as a prolonged physiological recovery period after an emotional stressor. Group differences after the 5-min recovery period suggest that children with migraine experience delayed sympathetic hyperarousal and prolonged sympathovagal imbalance. The treatment implications of these findings are discussed.
Authors: Cynthia W Karlson; Catrina C Litzenburg; Marilyn L Sampilo; Michael A Rapoff; Mark Connelly; Jennifer L Bickel; Andrew D Hershey; Scott W Powers Journal: Headache Date: 2013-09-19 Impact factor: 5.887
Authors: Markus Gerber; Katharina Endes; Serge Brand; Christian Herrmann; Flora Colledge; Lars Donath; Oliver Faude; Henner Hanssen; Uwe Pühse; Lukas Zahner Journal: Qual Life Res Date: 2016-12-08 Impact factor: 4.147