Maria Fagnano1, Kelly M Conn, Jill S Halterman. 1. Department of Pediatrics, University of Rochester School of Medicine and Dentistry, and Children's Hospital at Strong, Strong Memorial Hospital, Rochester, NY 14642, USA. maria_fagnano@urmc.rochester.edu
Abstract
OBJECTIVE: To explore the relationship between environmental tobacco smoke (ETS) exposure and behavior among inner-city children with significant asthma. METHODS: We analyzed baseline data for 200 children 4 to 10 years old who were enrolled in an asthma program. Environmental tobacco smoke exposure was measured by the child's salivary cotinine level. Caregivers completed the 28-item Behavior Problem Index (BPI). Positive responses were summed for a total BPI score, and children with scores >14 were considered to have significant behavior problems. We conducted Student t tests and multivariate regression analyses to determine the association of children's cotinine levels with BPI scores. RESULTS: Overall, 56% of children were male, 65% were black, and 72% had Medicaid. Mean cotinine level was 1.47 ng/mL. Overall, 30% of children had total BPI scores >14. Children with cotinine values >1.47 ng/mL had significantly higher scores compared with children with lower cotinine values on total BPI (12.5 vs 10.2), as well as externalizing (9.0 vs 7.2), antisocial (2.3 vs 1.7), and immature (2.1 vs 1.6) subscales. In a multivariate model, log cotinine remained independently associated with externalizing (P = .04), headstrong (P = .04), and antisocial behavior (P = .04). CONCLUSIONS: Cotinine levels are independently associated with problem behaviors among this sample of urban children with asthma.
OBJECTIVE: To explore the relationship between environmental tobacco smoke (ETS) exposure and behavior among inner-city children with significant asthma. METHODS: We analyzed baseline data for 200 children 4 to 10 years old who were enrolled in an asthma program. Environmental tobacco smoke exposure was measured by the child's salivary cotinine level. Caregivers completed the 28-item Behavior Problem Index (BPI). Positive responses were summed for a total BPI score, and children with scores >14 were considered to have significant behavior problems. We conducted Student t tests and multivariate regression analyses to determine the association of children's cotinine levels with BPI scores. RESULTS: Overall, 56% of children were male, 65% were black, and 72% had Medicaid. Mean cotinine level was 1.47 ng/mL. Overall, 30% of children had total BPI scores >14. Children with cotinine values >1.47 ng/mL had significantly higher scores compared with children with lower cotinine values on total BPI (12.5 vs 10.2), as well as externalizing (9.0 vs 7.2), antisocial (2.3 vs 1.7), and immature (2.1 vs 1.6) subscales. In a multivariate model, log cotinine remained independently associated with externalizing (P = .04), headstrong (P = .04), and antisocial behavior (P = .04). CONCLUSIONS:Cotinine levels are independently associated with problem behaviors among this sample of urban children with asthma.
Authors: M Kattan; H Mitchell; P Eggleston; P Gergen; E Crain; S Redline; K Weiss; R Evans; R Kaslow; C Kercsmar; F Leickly; F Malveaux; H J Wedner Journal: Pediatr Pulmonol Date: 1997-10
Authors: Jill S Halterman; Peter G Szilagyi; Susan G Fisher; Maria Fagnano; Paul Tremblay; Kelly M Conn; Hongyue Wang; Belinda Borrelli Journal: Arch Pediatr Adolesc Med Date: 2011-03
Authors: Hee Sun Yang; Hyungryul Lim; Jonghyuk Choi; Sanghyuk Bae; Yeni Kim; Ho-Jang Kwon; Mina Ha Journal: J Korean Med Sci Date: 2018-07-23 Impact factor: 2.153