Literature DB >> 1892244

Genetic mapping by single sperm typing.

N Arnheim1, H Li, X Cui.   

Abstract

The polymerase chain reaction makes it possible to analyse DNA sequences in a single cell and has led to a new approach for constructing genetic maps. We describe a procedure called 'sperm typing' which can accurately classify individual meiotic products as recombinant of non-recombinant. This permits the linkage relationships among DNA polymorphisms to be determined without pedigree analysis.

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Year:  1991        PMID： 1892244     DOI： 10.1111/j.1365-2052.1991.tb00652.x

Source DB:  PubMed          Journal:  Anim Genet        ISSN： 0268-9146            Impact factor:   3.169


  3 in total

1.  Genome screens using linkage disequilibrium tests: optimal marker characteristics and feasibility.

Authors:  N H Chapman; E M Wijsman
Journal:  Am J Hum Genet       Date:  1998-12       Impact factor: 11.025

2.  Reliable genotyping of samples with very low DNA quantities using PCR.

Authors:  P Taberlet; S Griffin; B Goossens; S Questiau; V Manceau; N Escaravage; L P Waits; J Bouvet
Journal:  Nucleic Acids Res       Date:  1996-08-15       Impact factor: 16.971

3.  Comparison of FISH PRINS, and conventional and fluorescent PCR for single-cell sexing: suitability for preimplantation genetic diagnosis.

Authors:  I Findlay; N Corby; A Rutherford; P Quirke
Journal:  J Assist Reprod Genet       Date:  1998-05       Impact factor: 3.412
  3 in total

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