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Literature DB >> 18912891

The inhibitory effect of polysaccharide on mumps virus multiplication.

Abstract

Polysaccharides derived from type-specific Friedländer bacilli cause inhibition of the multiplication of mumps virus in the allantoic sac of the chick embryo. As little as 5 microg. of polysaccharide is effective as an inhibitor. Inhibition of multiplication is obtained when polysaccharide is injected as long as 4 days after inoculation of virus. Chemical studies have shown that the structural configurations of the polysaccharide responsible for specific serological activity are not identical with those which determine the inhibitory effect relative to mumps virus. The possible mechanisms of the inhibition of viral multiplication by means of polysaccharides are discussed.

Entities: Chemical Species

Keywords: PAROTITIS; SACCHARIDES

Mesh：

Substances：

Year: 1948 PMID： 18912891 PMCID： PMC2135788 DOI： 10.1084/jem.87.5.385

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

17 in total

1. THE HEMOAGGLUTINATIVE PROPERTIES OF AMNIOTIC FLUID FROM EMBRYONATED EGGS INFECTED WITH MUMPS VIRUS.

Authors: J H Levens; J F Enders
Journal: Science Date: 1945-08-03 Impact factor: 47.728

2. Properties of a Virus Inactivator From Yeast.

Authors: W N Takahashi
Journal: Science Date: 1946-10-18 Impact factor: 47.728

3. THE SOLUBLE SPECIFIC SUBSTANCE OF A STRAIN OF FRIEDLANDER'S BACILLUS : PAPER I.

Authors: M Heidelberger; W F Goebel; O T Avery
Journal: J Exp Med Date: 1925-10-31 Impact factor: 14.307

4. CENTRIFUGATION AND ULTRAFILTRATION STUDIES ON ALLANTOIC FLUID PREPARATIONS OF INFLUENZA VIRUS.

Authors: W F Friedewald; E G Pickels
Journal: J Exp Med Date: 1944-03-01 Impact factor: 14.307

5. STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : III. HEMAGGLUTINATION BY THE VIRUS; THE OCCURRENCE OF COMBINATION BETWEEN THE VIRUS AND A TISSUE SUBSTANCE.

Authors: E C Curnen; F L Horsfall
Journal: J Exp Med Date: 1946-01-31 Impact factor: 14.307

6. THE SOLUBLE SPECIFIC SUBSTANCE OF FRIEDLANDER'S BACILLUS : III. ON THE ISOLATION AND PROPERTIES OF THE SPECIFIC CARBOHYDRATES FROM TYPES A AND C FRIEDLANDER BACILLUS.

Authors: W F Goebel; O T Avery
Journal: J Exp Med Date: 1927-09-30 Impact factor: 14.307

7. The effect of polysaccharides on the reaction between erythrocytes and viruses, with particular reference to mumps virus.

Authors: H S GINSBERG; W F GOEBEL; F L HORSFALL
Journal: J Exp Med Date: 1948-05-01 Impact factor: 14.307

8. THE MOUSE INFECTIVITY TITRATION OF INFLUENZA VIRUS.

Authors: M A Lauffer; G L Miller
Journal: J Exp Med Date: 1944-02-01 Impact factor: 14.307

9. A STUDY OF CONDITIONS FOR THE OPTIMUM PRODUCTION OF PR8 INFLUENZA VIRUS IN CHICK EMBRYOS.

Authors: G L Miller
Journal: J Exp Med Date: 1944-02-01 Impact factor: 14.307

10. INHIBITION BY CERTAIN POLYSACCHARIDES OF HEMAGGLUTINATION AND OF MULTIPLICATION OF INFLUENZA VIRUS.

Authors: R H Green; D W Woolley
Journal: J Exp Med Date: 1947-06-30 Impact factor: 14.307

22 in total

1. Inhibition of virus and T-haemagglutination by typhoid fever Vi-antigen.

Authors: V M ZHDANOV; S A DEMIDOVA; G J SVET-MOLDAVSKY
Journal: Bull World Health Organ Date: 1961 Impact factor: 9.408

2. [Protective effect of polysaccharide-like fractions of bacterial origin in an experimental virus infection].

Authors: F KRALDOLFER; R MEIER
Journal: Experientia Date: 1956-06-15

3. Mechanism of production of pulmonary lesions in mice by Newcastle disease virus (NDV).

Authors: H S GINSBERG
Journal: J Exp Med Date: 1951-09 Impact factor: 14.307

4. Therapy of infection with pneumonia virus of mice (PVM); effect of a polysaccharide on the multiplication cycles of the virus and on the course of the viral pneumonia.

Authors: H S GINSBERG; F L HORSFALL
Journal: J Exp Med Date: 1951-02 Impact factor: 14.307

5. Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts.

Authors: D C Helfgott; L T May; Z Sthoeger; I Tamm; P B Sehgal
Journal: J Exp Med Date: 1987-11-01 Impact factor: 14.307

6. Effect of sodium monofluoroacetate on the multiplication of influenza viruses, mumps virus and pneumonia virus of mice (PVM).

Authors: W J MOGABGAB; F L HORSFALL
Journal: J Exp Med Date: 1952-12 Impact factor: 14.307

7. Purification of an influenza virus substrate, and demonstration of its competitive antagonism to apple pectin.

Authors: D W WOOLLEY
Journal: J Exp Med Date: 1949-01 Impact factor: 14.307

8. The effect of polysaccharides on the reaction between erythrocytes and viruses, with particular reference to mumps virus.

Authors: H S GINSBERG; W F GOEBEL; F L HORSFALL
Journal: J Exp Med Date: 1948-05-01 Impact factor: 14.307

9. Formation of non-infectious influenza virus in mouse lungs: its dependence upon extensive pulmonary consolidation initiated by the viral inoculum.

Authors: H S GINSBERG
Journal: J Exp Med Date: 1954-12-01 Impact factor: 14.307

10. Factors related to the growth of psittacosis virus (strain 6BC). IV. Certain amino acids, vitamins, and other substances.

Authors: H R MORGAN
Journal: J Exp Med Date: 1954-05-01 Impact factor: 14.307