Literature DB >> 18911176

The influence of available fluid on the production of experimental hemoglobinuric nephrosis in rabbits.

J J LALICH.   

Abstract

The importance of previous dehydration on the production of hemoglobinuric nephrosis is substantiated. Hemoglobinuric nephrosis regularly occurred in rabbits 3 to 16 days following the injections of hemoglobin. Five of 15 animals died of fatal hemoglobinuric nephrosis; the combined kidney weight in these exceeded the weight of the kidneys of control rabbits and of those which survived. Additional observations, not previously made, are focal necrosis of the liver and pulmonary edema in some of the rabbits which died. A relationship was evident between the quantity of available fluid and the severity of the hemoglobinuric nephrosis which developed after injections of hemoglobin.

Entities:  

Keywords:  HEMOGLOBINURIA/etiology; NEPHROSIS/hemoglobinuric

Mesh：

Year:  1948        PMID： 18911176      PMCID： PMC2135768          DOI： 10.1084/jem.87.2.157

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  2 in total

1.  PROLONGED WATER DEPRIVATION IN THE DOG.

Authors:  J R Elkinton; M Taffel
Journal:  J Clin Invest       Date:  1942-11       Impact factor: 14.808

2.  THE INFLUENCE OF INJECTIONS OF HOMOLOGOUS HEMOGLOBIN ON THE KIDNEYS OF NORMAL AND DEHYDRATED ANIMALS.

Authors:  J J Lalich
Journal:  J Exp Med       Date:  1947-07-31       Impact factor: 14.307
  2 in total
  4 in total

1.  The role of aciduria in the development of hemoglobinuric nephrosis in dehydrated rabbits.

Authors:  J J LALICH; S I SCHWARTZ
Journal:  J Exp Med       Date:  1950-07-01       Impact factor: 14.307

2.  EXPERIMENTAL STUDIES IN ACUTE RENAL FAILURE. II. FINE STRUCTURE CHANGES IN TUBULES ASSOCIATED WITH RENAL FAILURE INDUCED BY GLOBIN.

Authors:  M G MENEFEE; C B MUELLER; T B MILLER; J K MYERS; A L BELL
Journal:  J Exp Med       Date:  1964-12-01       Impact factor: 14.307

3.  Effects of proteinuria on the kidney; proteinuria, renal enlargement, and renal injury consequent on protracted parenteral administration of protein solutions in rats.

Authors:  J H BAXTER; G C COTZIAS
Journal:  J Exp Med       Date:  1949-06-01       Impact factor: 14.307

4.  The renal lesion associated with hemoglobinemia. I. Its production and functional evolution in the rat.

Authors:  J R Jaenike
Journal:  J Exp Med       Date:  1966-03-01       Impact factor: 14.307
  4 in total

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