Literature DB >> 1888407

A study to compare the use of fusidic acid viscous eye drops and chloramphenicol eye ointment in an accident and emergency department.

M R James1, R Brogan, M Carew-McColl.   

Abstract

A total of 300 patients attending an Accident and Emergency department with ophthalmic complaints needing topical antibiotic treatment were treated with fucithalmic or chloramphenicol (chloromycetin). Their compliance and the incidence of side effects were assessed. There was a 70.3% response rate to the questionnaire. Of the patients 51.3% using fucithalmic completed the 5 day course compared with 37.2% of those taking chloramphenicol. However, no patients were found to have suffered as a result of failing to complete the course. The incidence of side effects was similar in both groups.

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Year:  1991        PMID: 1888407      PMCID: PMC1285754          DOI: 10.1136/emj.8.2.125

Source DB:  PubMed          Journal:  Arch Emerg Med        ISSN: 0264-4924


  7 in total

1.  Ophthalmic use of chloramphenicol.

Authors:  J D Stevens; G P Mission
Journal:  Lancet       Date:  1987-12-19       Impact factor: 79.321

2.  Intraocular penetration of fusidic acid with topical Fucithalmic.

Authors:  S Hansen
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1985 Oct-Dec       Impact factor: 2.441

3.  Fatal aplastic anemia following topical administration of ophthalmic chloramphenicol.

Authors:  F T Fraunfelder; G C Bagby; D J Kelly
Journal:  Am J Ophthalmol       Date:  1982-03       Impact factor: 5.258

4.  Chloramphenicol and aplastic anemia.

Authors:  A J Flach
Journal:  Am J Ophthalmol       Date:  1982-05       Impact factor: 5.258

5.  Chloramphenicol and aplastic anemia.

Authors:  M P Dutro
Journal:  Am J Ophthalmol       Date:  1981-12       Impact factor: 5.258

6.  Fusidic acid in acute conjunctivitis. Single-blind, randomized comparison of fusidic acid and chloramphenicol viscous eye drops.

Authors:  J Hvidberg
Journal:  Acta Ophthalmol (Copenh)       Date:  1987-02

7.  Fusidic acid in tear fluid: pharmacokinetic study with fusidic acid viscous eye drops.

Authors:  O P van Bijsterveld; H Andriesse; B H Nielsen
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1987 Jul-Sep       Impact factor: 2.441

  7 in total

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