Literature DB >> 1887471

Absence of antimalarial activity or interaction with mefloquine enantiomers in vitro of the main human metabolite of mefloquine.

L K Basco1, C Gillotin, F Gimenez, R Farinotti, J Le Bras.   

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Year:  1991        PMID： 1887471     DOI： 10.1016/0035-9203(91)90022-q

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN： 0035-9203            Impact factor:   2.184


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  3 in total

1.  Carboxymefloquine, the major metabolite of the antimalarial drug mefloquine, induces drug-metabolizing enzyme and transporter expression by activation of pregnane X receptor.

Authors:  Rita Piedade; Stefanie Traub; Andreas Bitter; Andreas K Nüssler; José P Gil; Matthias Schwab; Oliver Burk
Journal:  Antimicrob Agents Chemother       Date:  2014-10-13       Impact factor: 5.191

Review 2.  Stereoselectivity in the pharmacodynamics and pharmacokinetics of the chiral antimalarial drugs.

Authors:  Dion R Brocks; Reza Mehvar
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

3.  Falciparum malaria in eastern Thailand: a randomized trial of the efficacy of a single dose of mefloquine.

Authors:  A L Fontanet; B D Johnston; A M Walker; Y Bergqvist; U Hellgren; W Rooney
Journal:  Bull World Health Organ       Date:  1994       Impact factor: 9.408
  3 in total

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