Literature DB >> 1887359

Gingival hyperplasia: a side effect of nifedipine and diltiazem.

L Fattore1, M Stablein, G Bredfeldt, T Semla, M Moran, J M Doherty-Greenberg.   

Abstract

Currently, calcium channel blockers are being used increasingly for the treatment of hypertension in the elderly. Several case reports in the dental literature suggest that patients treated with the calcium channel blockers manifest gingival hyperplasia similar to that seen in patients taking phenytoin (Dilantin, Parke-Davis). A small study of 89 patients undertaken at the Westside Veterans Administration Medical Center, Chicago seems to indicate that nifedipine and diltiazem do indeed cause gingival hyperplasia. A total of 83% of the patients studied receiving nifedipine showed evidence of hyperplastic tissue and 74% of those on diltiazem were found to have hyperplastic tissue.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1887359     DOI： 10.1111/j.1754-4505.1991.tb00828.x

Source DB:  PubMed          Journal:  Spec Care Dentist        ISSN： 0275-1879


  10 in total

Review 1.  Gingival enlargement induced by drugs.

Authors:  L Brunet; J Miranda; M Farré; L Berini; C Mendieta
Journal:  Drug Saf       Date:  1996-09       Impact factor: 5.606

Review 2.  A comparative review of the adverse effects of calcium antagonists.

Authors:  H T Dougall; J McLay
Journal:  Drug Saf       Date:  1996-08       Impact factor: 5.606

3.  Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study.

Authors:  I Ieiri; W Goto; K Hirata; A Toshitani; S Imayama; Y Ohyama; H Yamada; K Ohtsubo; S Higuchi
Journal:  Eur J Clin Pharmacol       Date:  1995       Impact factor: 2.953

4.  Local Inflammation Alters MMP-2 and MMP-9 Gelatinase Expression Associated with the Severity of Nifedipine-Induced Gingival Overgrowth: a Rat Model Study.

Authors:  Wu-Li Li; Cheng-Hai Wu; Jun Yang; Min Tang; Long-Jie Chen; Shou-Liang Zhao
Journal:  Inflammation       Date:  2015-08       Impact factor: 4.092

Review 5.  Calcium channel blocker-induced gingival enlargement.

Authors:  R Livada; J Shiloah
Journal:  J Hum Hypertens       Date:  2013-06-06       Impact factor: 3.012

6.  Combination of inflammatory and amlodipine induced gingival overgrowth in a patient with cardiovascular disease.

Authors:  Mohan Kumar Pasupuleti; S V V S Musalaiah; M Nagasree; P Aravind Kumar
Journal:  Avicenna J Med       Date:  2013-07

7.  Is periodontal health a predictor of drug-induced gingival overgrowth? A cross-sectional study.

Authors:  Ruchi Banthia; Santosh Gupta; Priyank Banthia; Pallavi Singh; Sapna Raje; Navkiran Kaur
Journal:  Dent Res J (Isfahan)       Date:  2014-09

Review 8.  Drug-induced gingival overgrowth in cardiovascular patients.

Authors:  Lucija Bajkovec; Anna Mrzljak; Robert Likic; Ivan Alajbeg
Journal:  World J Cardiol       Date:  2021-04-26

9.  Efficacy of AZM therapy in patients with gingival overgrowth induced by Cyclosporine A: a systematic review.

Authors:  Marco Clementini; Gianluca Vittorini; Alessandro Crea; Maria Rosaria Gualano; Ludovica Antonella Macrì; Giorgio Deli; Giuseppe La Torre
Journal:  BMC Oral Health       Date:  2008-12-16       Impact factor: 2.757

10.  Gingival Enlargement Induced by Felodipine Resolves with a Conventional Periodontal Treatment and Drug Modification.

Authors:  Nabil Khzam; David Bailey; Helen S Yie; Mahmoud M Bakr
Journal:  Case Rep Dent       Date:  2016-02-29
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.