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Literature DB >> 18855993

Porphyria cutanea tarda as a complication of therapy for chronic hepatitis C.

James Azim¹, Heather McCurdy, Richard-H Moseley.

Abstract

There is a strong association between porphyria cutanea tarda (PCT) and chronic viral hepatitis C. Therapy for chronic viral hepatitis C may improve PCT. However, there are only a few reports of the de novo development of PCT during therapy for chronic viral hepatitis C. We describe the development of PCT in a 56-year-old patient with chronic viral hepatitis C after 12 wk of peginterferon/ribavirin therapy. In addition, the patient was homozygous for the H63D hereditary hemochromatosis gene (HFE) mutation. The association of PCT with chronic viral hepatitis C and the possible role of hepatic iron overload and ribavirin-induced hemolytic anemia in the development of PCT during therapy for chronic viral hepatitis C are discussed.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2008 PMID： 18855993 PMCID： PMC2751904 DOI： 10.3748/wjg.14.5913

Source DB: PubMed Journal: World J Gastroenterol ISSN： 1007-9327 Impact factor: 5.742

20 in total

1. Porphyria cutanea tarda during interferon/ribavirin therapy for chronic hepatitis C.

Authors: Wolfgang Jessner; Manon Der-Petrossian; Lene Christiansen; Harald Maier; Petra Steindl-Munda; Alfred Gangl; Peter Ferenci
Journal: Hepatology Date: 2002-11 Impact factor: 17.425

Review 2. Hepatic porphyrias: diagnosis and management.

Authors: Annie T Chemmanur; Herbert L Bonkovsky
Journal: Clin Liver Dis Date: 2004-11 Impact factor: 6.126

3. Ineffective interferon treatment of chronic hepatitis C-associated porphyria cutanea tarda, but with a transient decrease in HCV RNA levels.

Authors: M Furuta; M Kaito; E Gabazza; N Fujita; S Ishida; S Tamaki; R Ikeda; S Wakisawa; H Hayashi; S Watanabe; Y Adachi
Journal: J Gastroenterol Date: 2000 Impact factor: 7.527

Review 4. Prevalence of hepatitis C virus infection in porphyria cutanea tarda.

Authors: Silvia Fargion; Anna Ludovica Fracanzani
Journal: J Hepatol Date: 2003-10 Impact factor: 25.083

5. Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: role of membrane oxidative damage.

Authors: L De Franceschi; G Fattovich; F Turrini; K Ayi; C Brugnara; F Manzato; F Noventa; A M Stanzial; P Solero; R Corrocher
Journal: Hepatology Date: 2000-04 Impact factor: 17.425

Porphyria cutanea tarda as a complication of therapy for chronic hepatitis C.

1. Porphyria cutanea tarda during interferon/ribavirin therapy for chronic hepatitis C.

Review 2. Hepatic porphyrias: diagnosis and management.

3. Ineffective interferon treatment of chronic hepatitis C-associated porphyria cutanea tarda, but with a transient decrease in HCV RNA levels.

Review 4. Prevalence of hepatitis C virus infection in porphyria cutanea tarda.

5. Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: role of membrane oxidative damage.

6. Porphyria cutanea tarda remission.

Review 7. Genetic aspects of porphyria cutanea tarda.

Review 8. Prevalence of hepatitis C virus infection in porphyria cutanea tarda: systematic review and meta-analysis.

9. Increase in hepatic iron stores following prolonged therapy with ribavirin in patients with chronic hepatitis C.

10. Porphyria cutanea tarda, dermatomyositis and non-Hodgkin lymphoma in virus C infection.

Review 1. Hepatitis C, porphyria cutanea tarda and liver iron: an update.

2. Hepatitis C Treatment in Patients With Porphyria Cutanea Tarda.

Review 3. Cutaneous manifestations of hepatitis C in the era of new antiviral agents.

4. Hepatitis C- and HIV-induced porphyria cutanea tarda.