Probing interactions by means of pulsed field gradient nuclear magnetic resonance spectroscopy.

Molecular self-diffusion coefficients (D) of species in solution are related to size and shape and can be used for studying association phenomena. Pulsed field gradient nuclear magnetic resonance (PFG-NMR) spectroscopy has been revealed to be a powerful analytical tool for D measurement in different research fields. The present work briefly illustrates the use of PFG-NMR for assessing the existence of interactions in very different chemical systems: organic and organometallic compounds, colloidal materials and biological aggregates. The application of PFG-NMR is remarkable for understanding the role of anions in homogenous transition metal catalysis and for assessing the aggregation behaviour of biopolymers in material science.