Literature DB >> 18854967

[Single base polymorphisms and erectile dysfunction].

A Eisenhardt1, H Rübben, H Sperling.   

Abstract

The risk for erectile dysfunction is closely linked to cardiovascular morbidities such as coronary heart disease, arterial hypertension, hypercholesterolemia, and diabetes. Molecular analysis revealed an association between the genotypes in single base polymorphisms and the risk for these cardiovascular morbidities. In this review the current knowledge of association studies of single nucleotide polymorphisms and erectile dysfunction and the response to the PDE-5 inhibitor sildenafil is described.

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Year:  2008        PMID： 18854967     DOI： 10.1007/s00120-008-1800-8

Source DB:  PubMed          Journal:  Urologe A        ISSN： 0340-2592            Impact factor:   0.639


  21 in total

Review 1.  Vascular risk factors and erectile dysfunction.

Authors:  M E Sullivan; S R Keoghane; M A Miller
Journal:  BJU Int       Date:  2001-06       Impact factor: 5.588

2.  Association between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and erectile dysfunction in patients with metabolic syndrome.

Authors:  E B Mazo; S I Gamidov; M N Mamedov; V V Iremashvili
Journal:  Int J Impot Res       Date:  2007-08-02       Impact factor: 2.896

3.  Determination of human angiotensin converting enzyme (ACE) gene polymorphisms in erectile dysfunction: frequency differences of ACE gene polymorphisms according to the method of analysis.

Authors:  D S Kim; S I Choi; H S Lee; J K Park; H K Yi
Journal:  Clin Chem Lab Med       Date:  2001-01       Impact factor: 3.694

4.  Summary of the recommendations on sexual dysfunctions in men.

Authors:  Tom F Lue; François Giuliano; Francesco Montorsi; Raymond C Rosen; Karl-Erik Andersson; Stanley Althof; George Christ; Dimitrios Hatzichristou; Mark Hirsch; Yasasuke Kimoto; Ronald Lewis; Kevin McKenna; Chris MacMahon; Alvaro Morales; John Mulcahy; Harin Padma-Nathan; John Pryor; Inigo Saenz de Tejada; Ridwan Shabsigh; Gorm Wagner
Journal:  J Sex Med       Date:  2004-07       Impact factor: 3.802

5.  Cyclic AMP and cyclic GMP activate protein kinase G in cavernosal smooth muscle cells: old age is a negative factor.

Authors:  C-S Lin; X Liu; S Chow; T F Lue
Journal:  BJU Int       Date:  2002-04       Impact factor: 5.588

6.  Association of a human G-protein beta3 subunit variant with hypertension.

Authors:  W Siffert; D Rosskopf; G Siffert; S Busch; A Moritz; R Erbel; A M Sharma; E Ritz; H E Wichmann; K H Jakobs; B Horsthemke
Journal:  Nat Genet       Date:  1998-01       Impact factor: 38.330

7.  ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with erectile dysfunction.

Authors:  Andreas Eisenhardt; Herbert Sperling; Ekkehard Hauck; Hartmut Porst; Christian Stief; Herbert Rübben; Norbert Müller; Winfried Siffert
Journal:  Urology       Date:  2003-07       Impact factor: 2.649

8.  Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death.

Authors:  A J Marian; Q T Yu; R Workman; G Greve; R Roberts
Journal:  Lancet       Date:  1993-10-30       Impact factor: 79.321

9.  Glu298Asp endothelial nitric oxide synthase polymorphism is a risk factor for erectile dysfunction in the Mexican Mestizo population.

Authors:  Haydee Rosas-Vargas; Ramon M Coral-Vazquez; Rosario Tapia; Jose L Borja; Ricardo A Salas; Fabio Salamanca
Journal:  J Androl       Date:  2004 Sep-Oct

10.  A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease.

Authors:  K Lindpaintner; M A Pfeffer; R Kreutz; M J Stampfer; F Grodstein; F LaMotte; J Buring; C H Hennekens
Journal:  N Engl J Med       Date:  1995-03-16       Impact factor: 91.245
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