Literature DB >> 18854766

Do psychological attributes matter for adherence to antihypertensive medication? The Finnish Public Sector Cohort Study.

Hermann Nabi1, Jussi Vahtera, Archana Singh-Manoux, Jaana Pentti, Tuula Oksanen, David Gimeno, Marko Elovainio, Marianna Virtanen, Timo Klaukka, Mika Kivimaki.   

Abstract

OBJECTIVE: Psychological factors may be important determinants of adherence to antihypertensive medication, as they have been repeatedly found to be associated with an increased risk of hypertension, coronary heart disease, and health-damaging behaviours. We examined the importance of several psychological attributes (sense of coherence, optimism, pessimism, hostility, anxiety) with regard to antihypertensive medication adherence assessed by pharmacy refill records.
METHODS: A total of 1021 hypertensive participants, aged 26-63 years, who were employees in eight towns and 12 hospitals in Finland were included in the analyses.
RESULTS: We found 60% of patients to be totally adherent, 36% partially adherent, and 4% totally nonadherent. Multinomial regression analyses revealed high sense of coherence to be associated with lower odds of being totally nonadherent in contrast of being totally adherent (odds ratio=0.55; 95% confidence interval: 0.31-0.96). This association was independent of factors that influenced adherence to antihypertensive medication, such as sociodemographic characteristics, health-related behaviours, self-reported medical history of doctor-diagnosed comorbidity, and anteriority of hypertension status. The association was not specific to certain types of antihypertensive drugs.
CONCLUSION: High sense of coherence may influence antihypertensive medication-adherence behaviour. Aspects characterizing this psychological attribute, such as knowledge (comprehensibility), capacity (manageability), and motivation (meaningfulness) may be important determinants of adherence behaviour for asymptomatic illnesses, such as hypertension, in which patients often do not feel or perceive the immediate consequences of skipping medication doses.

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Year:  2008        PMID: 18854766      PMCID: PMC2784079          DOI: 10.1097/HJH.0b013e32830dfe5f

Source DB:  PubMed          Journal:  J Hypertens        ISSN: 0263-6352            Impact factor:   4.844


  32 in total

1.  Adherence to long-term therapies: evidence for action.

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2.  Long-term results, late complications and quality of life in a series of adjustable gastric banding.

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3.  The relationship between 'job strain,' workplace diastolic blood pressure, and left ventricular mass index. Results of a case-control study.

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4.  Validation of pharmacy records in drug exposure assessment.

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5.  The structure and properties of the sense of coherence scale.

Authors:  A Antonovsky
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6.  Relation of hostility to medication adherence, symptom complaints, and blood pressure reduction in a clinical field trial of antihypertensive medication.

Authors:  D Lee; C F Mendes de Leon; C D Jenkins; S H Croog; S Levine; A Sudilovsky
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10.  Adherence to long-term therapies: evidence for action.

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  12 in total

Review 1.  Factors associated with antihypertensive medication non-adherence: a systematic review.

Authors:  D M van der Laan; P J M Elders; C C L M Boons; J J Beckeringh; G Nijpels; J G Hugtenburg
Journal:  J Hum Hypertens       Date:  2017-06-29       Impact factor: 3.012

2.  Association between therapeutic alliance, care satisfaction, and pharmacological adherence in bipolar disorder.

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3.  Factors associated with non-adherence to three hypertension self-management behaviors: preliminary data for a new instrument.

Authors:  Matthew J Crowley; Janet M Grubber; Maren K Olsen; Hayden B Bosworth
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4.  Workplace social capital and adherence to antihypertensive medication: a cohort study.

Authors:  Tuula Oksanen; Ichiro Kawachi; Anne Kouvonen; Etsuji Suzuki; Soshi Takao; Noora Sjösten; Marianna Virtanen; Jaana Pentti; Jussi Vahtera; Mika Kivimäki
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5.  Obsessive-Compulsive and Post Traumatic Avoidance Symptoms Influence the Response to Antihypertensive Therapy: Relevance in Uncontrolled Hypertension.

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Journal:  Pharmaceuticals (Basel)       Date:  2009-11-16

Review 6.  Psychosocial predictors of non-adherence to chronic medication: systematic review of longitudinal studies.

Authors:  Hanneke E Zwikker; Bart J van den Bemt; Johanna E Vriezekolk; Cornelia H van den Ende; Sandra van Dulmen
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7.  Medication adherence: a review of pharmacy education, research, practice and policy in Finland.

Authors:  J Simon Bell; Hannes Enlund; Kirsti Vainio
Journal:  Pharm Pract (Granada)       Date:  2010-03-15

8.  Stress as a risk factor for noncompliance with treatment regimens in patients with diabetes and hypertension.

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9.  Sense of Coherence is associated with LDL-cholesterol in patients with type 1 diabetes - The PROLONG-Steno study.

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Review 10.  Optimism's Explicative Role for Chronic Diseases.

Authors:  Giulia Avvenuti; Ilaria Baiardini; Anna Giardini
Journal:  Front Psychol       Date:  2016-03-02
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