Literature DB >> 18854233

Beyond the big three: systematic analysis of virulence factors in Cryptococcus neoformans.

James Kronstad1, Won Hee Jung, Guanggan Hu.   

Abstract

The fungal pathogen Cryptococcus neoformans has three major virulence factors: growth at 37 degrees C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al. (2008) employed signature tagged mutagenesis to systematically identify virulence genes. Remarkably, mutations in many of these genes did not influence the major virulence traits.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18854233     DOI: 10.1016/j.chom.2008.09.003

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  12 in total

1.  The lysine biosynthetic enzyme Lys4 influences iron metabolism, mitochondrial function and virulence in Cryptococcus neoformans.

Authors:  Eunsoo Do; Minji Park; Guanggan Hu; Mélissa Caza; James W Kronstad; Won Hee Jung
Journal:  Biochem Biophys Res Commun       Date:  2016-06-25       Impact factor: 3.575

2.  Leu1 plays a role in iron metabolism and is required for virulence in Cryptococcus neoformans.

Authors:  Eunsoo Do; Guanggan Hu; Mélissa Caza; Debora Oliveira; James W Kronstad; Won Hee Jung
Journal:  Fungal Genet Biol       Date:  2014-12-29       Impact factor: 3.495

3.  The ZIP family zinc transporters support the virulence of Cryptococcus neoformans.

Authors:  Eunsoo Do; Guanggan Hu; Mélissa Caza; James W Kronstad; Won Hee Jung
Journal:  Med Mycol       Date:  2016-04-26       Impact factor: 4.076

Review 4.  The ER stress response and host temperature adaptation in the human fungal pathogen Cryptococcus neoformans.

Authors:  Virginia E Glazier; John C Panepinto
Journal:  Virulence       Date:  2013-11-19       Impact factor: 5.882

5.  The F-Box Protein Fbp1 Shapes the Immunogenic Potential of Cryptococcus neoformans.

Authors:  Jorge Masso-Silva; Vanessa Espinosa; Tong-Bao Liu; Yina Wang; Chaoyang Xue; Amariliz Rivera
Journal:  MBio       Date:  2018-01-09       Impact factor: 7.867

6.  Host Carbon Dioxide Concentration Is an Independent Stress for Cryptococcus neoformans That Affects Virulence and Antifungal Susceptibility.

Authors:  Damian J Krysan; Bing Zhai; Sarah R Beattie; Kara M Misel; Melanie Wellington; Xiaorong Lin
Journal:  mBio       Date:  2019-07-02       Impact factor: 7.867

7.  Autophagy Regulates Fungal Virulence and Sexual Reproduction in Cryptococcus neoformans.

Authors:  Su-Ting Jiang; An-Ni Chang; Lian-Tao Han; Jie-Shu Guo; Yuan-Hong Li; Tong-Bao Liu
Journal:  Front Cell Dev Biol       Date:  2020-05-25

8.  The Vacuolar Morphogenesis Protein Vam6-Like Protein Vlp1 Is Required for Pathogenicity of Cryptococcus neoformans.

Authors:  Cheng-Li Fan; Tong-Bao Liu
Journal:  J Fungi (Basel)       Date:  2021-05-27

9.  Genome-Wide Transcription Study of Cryptococcus neoformans H99 Clinical Strain versus Environmental Strains.

Authors:  Elaheh Movahed; Komathy Munusamy; Grace Min Yi Tan; Chung Yeng Looi; Sun Tee Tay; Won Fen Wong
Journal:  PLoS One       Date:  2015-09-11       Impact factor: 3.240

10.  A chemical genetic screen reveals a role for proteostasis in capsule and biofilm formation by Cryptococcus neoformans.

Authors:  François L Mayer; Eddy Sánchez-León; James W Kronstad
Journal:  Microb Cell       Date:  2018-10-31
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.