| Literature DB >> 18854149 |
Abstract
Spectraplakins are multifunctional proteins that interact with all three types of cytoskeletal filaments. In this issue, Wu et al. (2008) demonstrate a new actin-dependent ATPase activity for the spectraplakin ACF7 that allows it to guide microtubule ends along actin stress fibers to focal adhesions, promoting disassembly of adhesion contacts and hence cell movement.Entities:
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Year: 2008 PMID： 18854149 DOI： 10.1016/j.cell.2008.09.023
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582