| Literature DB >> 18854132 |
Abstract
In this issue of Developmental Cell, Layalle et al. reveal new insights into how nutrition controls body size in Drosophila. Nutrition specifically affects the activity of target of rapamycin (TOR) in the prothoracic gland. Under low-nutrition conditions, TOR suppresses ecdysone secretion--which otherwise terminates larval development--thereby prolonging growth and allowing larvae to still attain a near-normal body size.Entities:
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Year: 2008 PMID: 18854132 DOI: 10.1016/j.devcel.2008.09.014
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270