Literature DB >> 18852568

Ethical issues in psychopharmacology of children and adolescents.

Michael Koelch1, Kathleen Schnoor, Joerg M Fegert.   

Abstract

PURPOSE OF REVIEW: This summary of the literature published over recent years focuses on the ethical aspects of interventions with psychotropic medication in child and adolescent psychiatry. Ethical issues of pharmacotherapy concern aspects of research, safety, indicated use, enhancement, information and evidence-based practice. RECENT
FINDINGS: The literature on pharmacological interventions suggests changes in prescribing patterns for some substance classes owing to regulatory authorities' warnings. For most of the commonly used medications in children and adolescents no sound database about efficacy and safety is available and knowledge about adverse events and long-term safety remains poor. This is due to a general lack of clinical trials in this population. Legislative efforts have tried to improve safety and labelling of medicines for children. Ethical issues of enhancement in minors have been increasingly discussed over recent years.
SUMMARY: The ethical aspects of psychopharmacotherapy in minors are still rarely discussed in the literature. Practical questions of research and treatment ethics such as a need for information for children and parents are pointed out; conflicts of evocation and access to care for special populations in need are identified in a field lacking adequate ethical and clinical research.

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Year:  2008        PMID: 18852568     DOI: 10.1097/YCO.0b013e328314b776

Source DB:  PubMed          Journal:  Curr Opin Psychiatry        ISSN: 0951-7367            Impact factor:   4.741


  11 in total

1.  Mental health services for children of substance abusing parents: voices from the community.

Authors:  Laila F M Contractor; Karen L Celedonia; Mario Cruz; Antoine Douaihy; Jane N Kogan; Robert Marin; Bradley D Stein
Journal:  Community Ment Health J       Date:  2010-11-24

2.  Adolescents' commitment to continuing psychotropic medication: a preliminary investigation of considerations, contradictions, and correlates.

Authors:  Tally Moses
Journal:  Child Psychiatry Hum Dev       Date:  2011-02

3.  Detection and treatment of mental health issues by pediatric PCPs in New York State: an evaluation of Project TEACH.

Authors:  Bonnie D Kerker; Ka Ho Brian Chor; Kimberly E Hoagwood; Marleen Radigan; Matthew B Perkins; Jade Setias; Rui Wang; S Serene Olin; Sarah M Horwitz
Journal:  Psychiatr Serv       Date:  2014-12-15       Impact factor: 3.084

Review 4.  Ethics of pharmacological research involving adolescents.

Authors:  Eva Welisch; Luis A Altamirano-Diaz
Journal:  Paediatr Drugs       Date:  2015-02       Impact factor: 3.022

5.  Exercise to reduce the escalation of cocaine self-administration in adolescent and adult rats.

Authors:  Natalie E Zlebnik; Justin J Anker; Marilyn E Carroll
Journal:  Psychopharmacology (Berl)       Date:  2012-07-03       Impact factor: 4.530

6.  Is Medication Information for Children with Autism Spectrum Disorder Monitored and Coordinated Across Professionals? Findings from a Teacher Survey.

Authors:  Lynn K Koegel; Anna M Krasno; Howard Taras; Robert L Koegel; William Frea
Journal:  School Ment Health       Date:  2013-02-06

Review 7.  [Off-label use in child and adolescent psychiatry. An ongoing ethical, medical and legal problem].

Authors:  M Kölch; M Allroggen; J M Fegert
Journal:  Nervenarzt       Date:  2009-07       Impact factor: 1.214

8.  Drug development in pediatric psychiatry: current status, future trends.

Authors:  John S March; Joerg M Fegert
Journal:  Child Adolesc Psychiatry Ment Health       Date:  2012-02-07       Impact factor: 3.033

Review 9.  Sex Differences in Behavioral Dyscontrol: Role in Drug Addiction and Novel Treatments.

Authors:  Marilyn E Carroll; John R Smethells
Journal:  Front Psychiatry       Date:  2016-02-08       Impact factor: 4.157

10.  Drug monitoring in child and adolescent psychiatry for improved efficacy and safety of psychopharmacotherapy.

Authors:  Claudia Mehler-Wex; Michael Kölch; Julia Kirchheiner; Gisela Antony; Jörg M Fegert; Manfred Gerlach
Journal:  Child Adolesc Psychiatry Ment Health       Date:  2009-04-09       Impact factor: 3.033

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