Literature DB >> 18851153

Experimental observations of the squeezing-to-dripping transition in T-shaped microfluidic junctions.

Gordon F Christopher1, N Nadia Noharuddin, Joshua A Taylor, Shelley L Anna.   

Abstract

An experimental study of droplet breakup in T-shaped microfluidic junctions is presented in which the capillary number and flow rate ratio are varied over a wide range for several different viscosity ratios and several different ratios of the inlet channel widths. The range of conditions corresponds to the region in which both the squeezing pressure that arises when the emerging interface obstructs the channel and the viscous shear stress on the emerging interface strongly influence the process. In this regime, the droplet volume depends on the capillary number, the flow rate ratio, and the ratio of inlet channel widths, which controls the degree of confinement of the droplets. The viscosity ratio influences the droplet volume only when the viscosities are similar. When there is a large viscosity contrast in which the dispersed-phase liquid is at least 50 times smaller than the continuous-phase liquid, the resulting size is independent of the viscosity ratio and no transition to a purely squeezing regime appears. In this case, both the droplet volume and the droplet production frequency obey power-law behavior with the capillary number, consistent with expectations based on mass conservation of the dispersed-phase liquid. Finally, scaling arguments are presented that result in predicted droplet volumes that depend on the capillary number, flow rate ratio, and width ratio in a qualitatively similar way to that observed in experiments.

Year:  2008        PMID: 18851153     DOI: 10.1103/PhysRevE.78.036317

Source DB:  PubMed          Journal:  Phys Rev E Stat Nonlin Soft Matter Phys        ISSN: 1539-3755


  17 in total

1.  A lattice Boltzmann study of the effects of viscoelasticity on droplet formation in microfluidic cross-junctions.

Authors:  Anupam Gupta; Mauro Sbragaglia
Journal:  Eur Phys J E Soft Matter       Date:  2016-01-25       Impact factor: 1.890

2.  Effects of viscoelasticity on droplet dynamics and break-up in microfluidic T-Junctions: a lattice Boltzmann study.

Authors:  Anupam Gupta; Mauro Sbragaglia
Journal:  Eur Phys J E Soft Matter       Date:  2016-01-27       Impact factor: 1.890

3.  A novel method for producing unequal sized droplets in micro- and nanofluidic channels.

Authors:  Ahmad Bedram; Ali Moosavi; Siamak Kazemzadeh Hannani
Journal:  Eur Phys J E Soft Matter       Date:  2015-09-11       Impact factor: 1.890

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Journal:  Lab Chip       Date:  2017-05-31       Impact factor: 6.799

5.  Dripping and jetting in microfluidic multiphase flows applied to particle and fiber synthesis.

Authors:  J K Nunes; S S H Tsai; J Wan; H A Stone
Journal:  J Phys D Appl Phys       Date:  2013-03-20       Impact factor: 3.207

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Journal:  Anal Chem       Date:  2010-07-01       Impact factor: 6.986

7.  On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials.

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Journal:  Lab Chip       Date:  2019-04-24       Impact factor: 6.799

Review 8.  Therapeutic strategies based on polymeric microparticles.

Authors:  C Vilos; L A Velasquez
Journal:  J Biomed Biotechnol       Date:  2012-05-16

Review 9.  Droplets formation and merging in two-phase flow microfluidics.

Authors:  Hao Gu; Michel H G Duits; Frieder Mugele
Journal:  Int J Mol Sci       Date:  2011-04-15       Impact factor: 5.923

10.  Manipulation of single cells inside nanoliter water droplets using acoustic forces.

Authors:  Michael S Gerlt; Dominik Haidas; Alexandre Ratschat; Philipp Suter; Petra S Dittrich; Jürg Dual
Journal:  Biomicrofluidics       Date:  2020-12-18       Impact factor: 2.800

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