Various 1,1-disubstituted terminal olefins have been investigated for asymmetric epoxidation using chiral ketone catalysts. Up to 88% ee has been achieved with a lactam ketone, and a planar transition state is likely to be a major reaction pathway.
Various 1,1-disubstituted terminal n class="Chemical">olefins have been investigated for asymmetric epoxidation using chiral ketone catalysts. Up to 88% ee has been achieved with a lactam ketone, and a planar transition state is likely to be a major reaction pathway.
Authors: P C Page; G A Rassias; D Barros; A Ardakani; B Buckley; D Bethell; T A Smith; A M Slawin Journal: J Org Chem Date: 2001-10-19 Impact factor: 4.354
Authors: Philip C Bulman Page; David Barros; Benjamin R Buckley; Adel Ardakani; Brian A Marples Journal: J Org Chem Date: 2004-05-14 Impact factor: 4.354
Authors: Brandon A Vara; Thomas J Struble; Weiwei Wang; Mark C Dobish; Jeffrey N Johnston Journal: J Am Chem Soc Date: 2015-06-03 Impact factor: 15.419