| Literature DB >> 18850613 |
Sheetal Dhar1, E Maheswara Reddy, Anjali Shiras, Varsha Pokharkar, B L V Prasad.
Abstract
"Gellan Gum", widely used in food and confectionary industry as a thickening and gelling agent, has been employed as a reducing and stabilizing agent for the synthesis of gold nanoparticles. These nanoparticles display greater stability to electrolyte addition and pH changes relative to the traditional citrate and borohydride reduced nanoparticles. Subsequently these have been used to load anthracycline ring antibiotic doxorubicin hydrochloride. The drug loaded on these nanoparticles showed enhanced cytotoxic effects on human glioma cell lines LN-18 and LN-229.Entities:
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Year: 2008 PMID: 18850613 DOI: 10.1002/chem.200801093
Source DB: PubMed Journal: Chemistry ISSN: 0947-6539 Impact factor: 5.236