Literature DB >> 18850078

[The treatment of malignant tumors on venous leg ulcers. Case presentation and literature review].

W Lehnert1, K Kohl, H Riebe, M Jünger, A Ladwig.   

Abstract

Malignant changes in persistent venous leg ulcers are a grave complication of chronic impaired wound healing. In our case, a venous leg ulcer had persisted on the right calf for 30 years. Exophytic tumors in the ulcer with frequent bleeding prompted biopsies. A squamous cell carcinoma was found, but only in the second biopsy. The surgical procedure was planned so that in a single session both the tumor and the underlying causes of the chronic venous insufficiency in the leg could be treated appropriately. Extirpation of the enlarged lymph nodes in the groin was combined with crossectomy and removal of the long saphenous vein, followed by circular radial excision of the ulcer scar fascia (fasciotomy). The excised tissue was examined histologically. Muscle biopsies were taken from the site of suspicious adhesions of the fascia to the calf muscle. The large, circular defects on the lower leg were covered with the appropriate dressing to condition the wound bed. After three weeks the well-granulated area was covered with meshed split skin grafts. During the operation and in the post-operative phase, machine-assisted and manual decongestion was performed, an established therapy for lymphedema, chronic venous insufficiency and chronic venous ulcers.

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Year:  2008        PMID: 18850078     DOI: 10.1007/s00105-008-1593-0

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  12 in total

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Journal:  Hautarzt       Date:  1961-12       Impact factor: 0.751

Review 2.  Early diagnosis is vital in the management of squamous cell carcinomas associated with chronic non healing ulcers: a case series and review of the literature.

Authors:  Stuart Enoch; David R Miller; Patricia E Price; Keith G Harding
Journal:  Int Wound J       Date:  2004-09       Impact factor: 3.315

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Authors:  C Riess
Journal:  Hautarzt       Date:  1989-09       Impact factor: 0.751

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Authors:  D Yang; B D Morrison; Y K Vandongen; A Singh; M C Stacey
Journal:  Med J Aust       Date:  1996-06-17       Impact factor: 7.738

7.  Prognostic and therapeutic use of microstaging of cutaneous squamous cell carcinoma of the trunk and extremities.

Authors:  H I Friedman; P H Cooper; H J Wanebo
Journal:  Cancer       Date:  1985-09-01       Impact factor: 6.860

Review 8.  Leg ulcers and squamous cell carcinoma. An epidemiological study and a review of the literature.

Authors:  B Baldursson; B Sigurgeirsson; B Lindelöf
Journal:  Acta Derm Venereol       Date:  1993-06       Impact factor: 4.437

9.  Nonhealing leg ulcers: a manifestation of basal cell carcinoma.

Authors:  T J Phillips; S M Salman; G S Rogers
Journal:  J Am Acad Dermatol       Date:  1991-07       Impact factor: 11.527

10.  Neoplastic disease occurring in varicose ulcers or eczema: a report of six cases.

Authors:  W BLACK
Journal:  Br J Cancer       Date:  1952-06       Impact factor: 7.640

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  2 in total

Review 1.  Impaired wound healing: facts and hypotheses for multi-professional considerations in predictive, preventive and personalised medicine.

Authors:  Eden Avishai; Kristina Yeghiazaryan; Olga Golubnitschaja
Journal:  EPMA J       Date:  2017-03-03       Impact factor: 6.543

2.  [Parallels between wound healing, chronic inflammatory skin diseases and neoplasia: clinical aspects].

Authors:  A Brown; I Tantcheva-Poor; S A Eming
Journal:  Hautarzt       Date:  2014-11       Impact factor: 0.751

  2 in total

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