Alicia Ferreira1, Chris Garvey2, Gerilynn L Connors3, Lana Hilling4, Julia Rigler2, Susan Farrell3, Cindy Cayou4, Cyrus Shariat5, Harold R Collard6. 1. Department of Medicine, University of California San Francisco, San Francisco, CA. 2. Department of Pulmonary and Cardiac Rehabilitation, Seton Medical Center Pulmonary Rehabilitation, Daly City, CA. 3. INOVA Fairfax Hospital Lung Health Services, Falls Church, VA. 4. John Muir Health Lung Health Services, Concord, CA. 5. Department of Medicine, New York University, New York, NY. 6. Department of Medicine, University of California San Francisco, San Francisco, CA. Electronic address: hal.collard@ucsf.edu.
Abstract
BACKGROUND: Data examining the role of pulmonary rehabilitation (PR) in interstitial lung disease (ILD) are limited. We tested the hypothesis that PR can improve functional status and dyspnea in a large group of patients with ILD, and that certain baseline patient variables can predict this improvement. METHODS: Data from patients who were referred to PR with a diagnosis of ILD were included. Baseline and post-PR variables were recorded, and changes in 6-min walk test (6MWT) distance and dyspnea were evaluated. The impact of baseline variables on change in 6MWT distance and dyspnea were analyzed. RESULTS: A statistically significant difference was seen in both the change in Borg score and 6MWT distance after PR (p < 0.0001). These changes were consistent with previously established clinically significant differences. Baseline 6MWT distance was a significant predictor of change in 6MWT distance (p < 0.0001), with increasing baseline 6MWT distance predicting a smaller improvement after PR. CONCLUSIONS: These results suggest that PR should be considered as a standard of care for patients with ILD.
BACKGROUND: Data examining the role of pulmonary rehabilitation (PR) in interstitial lung disease (ILD) are limited. We tested the hypothesis that PR can improve functional status and dyspnea in a large group of patients with ILD, and that certain baseline patient variables can predict this improvement. METHODS: Data from patients who were referred to PR with a diagnosis of ILD were included. Baseline and post-PR variables were recorded, and changes in 6-min walk test (6MWT) distance and dyspnea were evaluated. The impact of baseline variables on change in 6MWT distance and dyspnea were analyzed. RESULTS: A statistically significant difference was seen in both the change in Borg score and 6MWT distance after PR (p < 0.0001). These changes were consistent with previously established clinically significant differences. Baseline 6MWT distance was a significant predictor of change in 6MWT distance (p < 0.0001), with increasing baseline 6MWT distance predicting a smaller improvement after PR. CONCLUSIONS: These results suggest that PR should be considered as a standard of care for patients with ILD.
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