The Drosophila system has proven a powerful tool to help unlock the regulatory processes that occur during specification and differentiation of the embryonic heart. In this review, we focus upon a temporal analysis of the molecular events that result in heart formation in Drosophila, with a particular emphasis upon how genomic and other cutting-edge approaches are being brought to bear upon the subject. We anticipate that systems-level approaches will contribute greatly to our comprehension of heart development and disease in the animal kingdom.
The pan class="Species">Drosophila system has proven a powerful tool to help unlock the regulatory processes that occur during specification and differentiation of the embryonic heart. In this review, we focus upon a temporal analysis of the molecular pan class="Gene">events that result in heart formation in Drosophila, with a particular emphasis upon how genomic and other cutting-edge approaches are being brought to bear upon the subject. We anticipate that systems-level approaches will contribute greatly to our comprehension of heart development and disease in the animal kingdom.
Authors: Shaad M Ahmad; Terese R Tansey; Brian W Busser; Michael T Nolte; Neal Jeffries; Stephen S Gisselbrecht; Nasser M Rusan; Alan M Michelson Journal: Dev Cell Date: 2012-07-17 Impact factor: 12.270
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Authors: Gloriana V Trujillo; Dalea H Nodal; Candice V Lovato; Jill D Hendren; Lynda A Helander; TyAnna L Lovato; Rolf Bodmer; Richard M Cripps Journal: Dev Biol Date: 2016-03-13 Impact factor: 3.582