| Literature DB >> 18846198 |
Louis A Carpino1, Adel Ali Abdel-Maksoud, E M E Mansour, Mohamed A Zewail.
Abstract
A model [6 + 5] segment coupling process involving a C-terminal valine hexapeptide acid and a resin-attached pentapeptide amide which N-terminated in a hindered Aib unit was examined using a variety of HOAt-derived coupling reagents. Best results were observed with HAPyU in DCM solvent in which loss of configuration amounted to 5.8%.Entities:
Year: 2007 PMID： 18846198 PMCID： PMC2344146 DOI： 10.1016/j.tetlet.2007.07.215
Source DB: PubMed Journal: Tetrahedron Lett ISSN： 0040-4039 Impact factor: 2.415