| Literature DB >> 18845580 |
Anna Ramírez-Soriano1, Francesc Calafell.
Abstract
UNLABELLED: We have developed a software that applies ascertainment bias on simulated DNA sequences and calculates F(ST) on them, so they can be used to generate neutral distributions that are appropriate to test whether the genetic differentiation of a particular gene between populations is compatible with neutral evolution, or, on the contrary, suggests local adaptation by natural selection. AVAILABILITY: FABSIM is available from http://www.snpator.com/public/downloads/aRamirez/FABSIM/.Mesh：
Year: 2008 PMID： 18845580 DOI： 10.1093/bioinformatics/btn531
Source DB: PubMed Journal: Bioinformatics ISSN： 1367-4803 Impact factor: 6.937