Literature DB >> 18845398

Burn healing is dependent on burn site: a quantitative analysis from a porcine burn model.

Xue-Qing Wang1, Pei-Yun Liu, Margit Kempf, Leila Cuttle, Allen Hong-En Chang, Michael Wong, Olena Kravchuk, Julie Mill, Roy M Kimble.   

Abstract

This retrospective review examines healing in different sites on a porcine burn model; 24 pairs of burns on 18 pigs from other animal trials were selected for analysis. Each pair of burns was located on the either the cranial or the caudal part of the thoracic ribs region, on the same side of the animal. The burns were 40-50 cm(2) in size and of uniform deep-dermal partial thickness. Caudal burns healed significantly better than cranial burns, demonstrated by earlier closure of wounds, less scar formation and better cosmesis. To our knowledge, this is the first detailed study reporting that burn healing is affected by location on a porcine burn model. We recommend that similar symmetrical burns should be used for future comparative assessments of burn healing.

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Year:  2008        PMID: 18845398     DOI: 10.1016/j.burns.2008.05.030

Source DB:  PubMed          Journal:  Burns        ISSN: 0305-4179            Impact factor:   2.744


  8 in total

1.  The effect of nano-scale topography on keratinocyte phenotype and wound healing following burn injury.

Authors:  Leigh G Parkinson; Suzanne M Rea; Andrew W Stevenson; Fiona M Wood; Mark W Fear
Journal:  Tissue Eng Part A       Date:  2011-12-08       Impact factor: 3.845

2.  How to create burn porcine models: a systematic review.

Authors:  A Wardhana; R F M Lumbuun; D Kurniasari
Journal:  Ann Burns Fire Disasters       Date:  2018-03-31

3.  Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.

Authors:  Randolph Stone; Emily C Saathoff; David A Larson; John T Wall; Nathan A Wienandt; Skuli Magnusson; Hilmar Kjartansson; Shanmugasundaram Natesan; Robert J Christy
Journal:  Int J Mol Sci       Date:  2021-02-04       Impact factor: 5.923

4.  Initial Characterization of the Pig Skin Bacteriome and Its Effect on In Vitro Models of Wound Healing.

Authors:  Matthew K McIntyre; Trent J Peacock; Kevin S Akers; David M Burmeister
Journal:  PLoS One       Date:  2016-11-08       Impact factor: 3.240

5.  Effect of Relaxin Expressing Adenovirus on Scar Remodeling: A Preliminary Study.

Authors:  Bok Ki Jung; Won Jai Lee; Eunhye Kang; Hyo Min Ahn; Yong Oock Kim; Dong Kyun Rah; Chae-Ok Yun; In Sik Yun
Journal:  Arch Craniofac Surg       Date:  2017-03-25

6.  Effect of Relaxin Expression from an Alginate Gel-Encapsulated Adenovirus on Scar Remodeling in a Pig Model.

Authors:  In Sik Yun; Eunhye Kang; Hyo Min Ahn; Yong Oock Kim; Dong Kyun Rah; Tai Suk Roh; Won Jai Lee; Chae Ok Yun
Journal:  Yonsei Med J       Date:  2019-09       Impact factor: 2.759

7.  Development of a Consistent and Reproducible Porcine Scald Burn Model.

Authors:  Christine J Andrews; Margit Kempf; Roy Kimble; Leila Cuttle
Journal:  PLoS One       Date:  2016-09-09       Impact factor: 3.240

8.  Delivery of Allogeneic Adipose Stem Cells in Polyethylene Glycol-Fibrin Hydrogels as an Adjunct to Meshed Autografts After Sharp Debridement of Deep Partial Thickness Burns.

Authors:  David M Burmeister; Randolph Stone; Nicole Wrice; Alfred Laborde; Sandra C Becerra; Shanmugasundaram Natesan; Robert J Christy
Journal:  Stem Cells Transl Med       Date:  2018-02-18       Impact factor: 6.940

  8 in total

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