Literature DB >> 18844841

Calcitriol and energy metabolism.

Michael B Zemel1, Xiaocun Sun.   

Abstract

Calcitriol, a calcitrophic hormone that can be suppressed by high dietary calcium, favors fatty acid synthesis and inhibits lipolysis via non-genomic modulation of Ca(2+) influx. Calcitriol also suppresses UCP2 expression via the nVDR and thereby increases energy efficiency. Calcitriol exerts a dose-dependent impact on adipocyte apoptosis and regulates adipose tissue fat depot location and expansion by promoting glucocorticoid production and release. Recent data also demonstrate a pivotal role of calcitriol in the modulation of cytokines, with potential roles in energy metabolism in adipocytes, macrophages, and skeletal muscle.

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Year:  2008        PMID： 18844841     DOI： 10.1111/j.1753-4887.2008.00099.x

Source DB:  PubMed          Journal:  Nutr Rev        ISSN： 0029-6643            Impact factor:   7.110


  19 in total

1.  A potential role for adjunctive vitamin D therapy in the management of weight gain and metabolic side effects of second-generation antipsychotics.

Authors:  Benjamin U Nwosu; Bruce Meltzer; Louise Maranda; Carol Ciccarelli; Daniel Reynolds; Laura Curtis; Jean King; Jean A Frazier; Mary M Lee
Journal:  J Pediatr Endocrinol Metab       Date:  2011       Impact factor: 1.634

2.  Differential effects of 1α,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes.

Authors:  Silvia Lorente-Cebrián; Anna Eriksson; Thomas Dunlop; Niklas Mejhert; Ingrid Dahlman; Gaby Aström; Eva Sjölin; Kerstin Wåhlén; Carsten Carlberg; Jurga Laurencikiene; Per Hedén; Peter Arner; Mikael Rydén
Journal:  Eur J Nutr       Date:  2011-06-24       Impact factor: 5.614

Review 3.  Vitamin D deficiency and toxicity in chronic kidney disease: in search of the therapeutic window.

Authors:  Uwe Querfeld; Robert H Mak
Journal:  Pediatr Nephrol       Date:  2010-06-22       Impact factor: 3.714

4.  Cardiovascular effects of calcium supplementation.

Authors:  I R Reid; M J Bolland; A Avenell; A Grey
Journal:  Osteoporos Int       Date:  2011-03-16       Impact factor: 4.507

5.  Milk intakes are not associated with percent body fat in children from ages 10 to 13 years.

Authors:  Sabrina E Noel; Andrew R Ness; Kate Northstone; Pauline Emmett; P K Newby
Journal:  J Nutr       Date:  2011-09-21       Impact factor: 4.798

6.  Supplementing alpha-tocopherol (vitamin E) and vitamin D3 in high fat diet decrease IL-6 production in murine epididymal adipose tissue and 3T3-L1 adipocytes following LPS stimulation.

Authors:  Fábio S Lira; José C Rosa; Claudio A Cunha; Eliane B Ribeiro; Claudia Oller do Nascimento; Lila M Oyama; João F Mota
Journal:  Lipids Health Dis       Date:  2011-02-27       Impact factor: 3.876

7.  Effects of dairy consumption on SIRT1 and mitochondrial biogenesis in adipocytes and muscle cells.

Authors:  Antje Bruckbauer; Michael B Zemel
Journal:  Nutr Metab (Lond)       Date:  2011-12-20       Impact factor: 4.169

8.  A high calcium diet containing nonfat dry milk reduces weight gain and associated adipose tissue inflammation in diet-induced obese mice when compared to high calcium alone.

Authors:  Anthony P Thomas; Tamara N Dunn; Josephine B Drayton; Pieter J Oort; Sean H Adams
Journal:  Nutr Metab (Lond)       Date:  2012-01-23       Impact factor: 4.169

Review 9.  Postprandial energy metabolism in the regulation of body weight: is there a mechanistic role for dietary calcium?

Authors:  Mario J Soares; Wendy L Chan She-Ping-Delfos
Journal:  Nutrients       Date:  2010-05-28       Impact factor: 5.717

Review 10.  Lipophilic micronutrients and adipose tissue biology.

Authors:  Jean-François Landrier; Julie Marcotorchino; Franck Tourniaire
Journal:  Nutrients       Date:  2012-11-06       Impact factor: 5.717
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