Literature DB >> 18843392

Synthesis of 8-bromo-, 8-methyl- and 8-phenyl-dATP and their polymerase incorporation into DNA.

Hana Cahová1, Radek Pohl, Lucie Bednárová, Katerina Nováková, Josef Cvacka, Michal Hocek.   

Abstract

dATP derivatives bearing Br, Me or Ph groups in position 8 were prepared and tested as substrates for DNA polymerases to show that 8-Br-dATP and 8-Me-dATP were efficiently incorporated, while 8-Ph-dATP was a poor substrate due to its bulky Ph group.

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Year:  2008        PMID： 18843392     DOI： 10.1039/b811935j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  Fluorescent 5-Pyrimidine and 8-Purine Nucleosides Modified with an N-Unsubstituted 1,2,3-Triazol-4-yl Moiety.

Authors:  Zhiwei Wen; Paloma R Tuttle; A Hasan Howlader; Anna Vasilyeva; Laura Gonzalez; Antonija Tangar; Ruipeng Lei; Eduardo E Laverde; Yuan Liu; Jaroslava Miksovska; Stanislaw F Wnuk
Journal:  J Org Chem       Date:  2019-03-06       Impact factor: 4.354

2.  Cross-coupling reaction with lithium methyltriolborate.

Authors:  Yasunori Yamamoto; Kazuya Ikizakura; Hajime Ito; Norio Miyaura
Journal:  Molecules       Date:  2012-12-28       Impact factor: 4.411

3.  N4-acyl-2'-deoxycytidine-5'-triphosphates for the enzymatic synthesis of modified DNA.

Authors:  Jevgenija Jakubovska; Daiva Tauraite; Lukas Birštonas; Rolandas Meškys
Journal:  Nucleic Acids Res       Date:  2018-07-06       Impact factor: 16.971

4.  Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases.

Authors:  Hana Macícková-Cahová; Michal Hocek
Journal:  Nucleic Acids Res       Date:  2009-12       Impact factor: 16.971
  4 in total

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