Literature DB >> 18841913

Enantioselective synthesis of indolizidine alkaloid trans-209D.

Carlos Alegret1, Antoni Riera.   

Abstract

(S)-N-Boc-baikiain, readily accessible from enantiomerically enriched 2,3-epoxy-5-hexen-1-ol 4 (prepared by Sharpless asymmetric epoxidation), was used as the starting material in the synthesis of indolizidine alkaloid trans-209D , which was obtained in 13 steps and 14% yield from 1 (5% from 4).

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Year:  2008        PMID: 18841913     DOI: 10.1021/jo801645p

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

Review 1.  Synthetic applications of chiral unsaturated epoxy alcohols prepared by sharpless asymmetric epoxidation.

Authors:  Antoni Riera; María Moreno
Journal:  Molecules       Date:  2010-02-23       Impact factor: 4.411

  1 in total

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