Literature DB >> 18841903

Lignans from the roots of Saururus chinensis.

Chang-Seob Seo1, Ming-Shan Zheng, Mi-Hee Woo, Chong-Soon Lee, Sung-Ho Lee, Byeong-Seon Jeong, Hyeun-Wook Chang, Yurngdong Jahng, Eung-Seok Lee, Jong-Keun Son.   

Abstract

Four new lignans, saucerneol F (1), saucerneol G (2), saucerneol H (3), and saucerneol I (4), were isolated from the EtOAc extract of the roots of Saururus chinensis, together with one known compound, saucerneol D (5). The structures of compounds 1-4 were elucidated by spectroscopic analysis. These compounds showed cytotoxic activities against HT-29, MCF-7, and HepG-2 cell lines.

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Year:  2008        PMID: 18841903     DOI: 10.1021/np8002723

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  2 in total

1.  Saucerneol F, a New Lignan Isolated from Saururus chinensis, Attenuates Degranulation via Phospholipase Cγ 1 Inhibition and Eicosanoid Generation by Suppressing MAP Kinases in Mast Cells.

Authors:  Yue Lu; Jong-Keun Son; Hyeun Wook Chang
Journal:  Biomol Ther (Seoul)       Date:  2012-11       Impact factor: 4.634

2.  Anti-Inflamatory Activity of Neolignan Compound Isolated from the Roots of Saururus chinensis.

Authors:  Sae-Rom Yoo; Hyekyung Ha; Hyeun-Kyoo Shin; Chang-Seob Seo
Journal:  Plants (Basel)       Date:  2020-07-23
  2 in total

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