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Literature DB >> 18841878

Proteomic analysis of the hyaloid vascular system regression during ocular development.

Elena Albè¹, Jin-Hong Chang, Nathalie F Azar, Alexander R Ivanov, Dimitri T Azar.

Abstract

We describe a proteomic approach to investigate the differential protein expression patterns and identify the physiologically relevant angiogenic and antiangiogenic factors involved in the hyaloid vascular system regression. Differentially expressed proteins were identified using two-dimensional gel electrophoresis followed by nanoflow chromatography coupled with tandem mass spectrometry. These proteins are expected to provide insight as to their function in the early maintenance and eventual regression of the hyaloid vascular system.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Proteome

Year: 2008 PMID： 18841878 PMCID： PMC2662928 DOI： 10.1021/pr800551m

Source DB: PubMed Journal: J Proteome Res ISSN： 1535-3893 Impact factor: 4.466

44 in total

1. Role of INK4a locus in normal eye development and cataract genesis.

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2. Kininostatin associates with membrane rafts and inhibits alpha(v)beta3 integrin activation in human umbilical vein endothelial cells.

Authors: Yi Wu; Victor Rizzo; Yuchuan Liu; Irma M Sainz; Noah G Schmuckler; Robert W Colman
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3. Kininogen binding to the surfaces of macrophages.

Authors: Anna Barbasz; Ibeth Guevara-Lora; Maria Rapala-Kozik; Andrzej Kozik
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4. PWWP module of human hepatoma-derived growth factor forms a domain-swapped dimer with much higher affinity for heparin.

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Journal: J Mol Biol Date: 2007-01-09 Impact factor: 5.469

Review 5. Survival factors, intracellular signal transduction, and the activation of endonucleases in apoptosis.

Authors: A Eastman
Journal: Semin Cancer Biol Date: 1995-02 Impact factor: 15.707

6. The inhibition of tube formation in a collagen-fibrinogen, three-dimensional gel by cleaved kininogen (HKa) and HK domain 5 (D5) is dependent on Src family kinases.

Authors: Yuchuan Liu; Irma M Sainz; Yi Wu; Robin Pixley; Ricardo G Espinola; Sarmina Hassan; Mohammad M Khan; Robert W Colman
Journal: Exp Cell Res Date: 2007-10-18 Impact factor: 3.905

7. Proteomic differentiation between murine retinal and brain-derived progenitor cells.

Authors: Tyra E Dunn-Thomas; Drena L Dobbs; Donald S Sakaguchi; Michael J Young; Vasant G Honovar; M Heather West Greenlee
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8. Development of a microarray chip for gene expression in rabbit ocular research.

Authors: Michael P Popp; Li Liu; Adrian Timmers; Douglas W Esson; Lineu Shiroma; Craig Meyers; Scott Berceli; Ming Tao; Graeme Wistow; Gregory S Schultz; Mark B Sherwood
Journal: Mol Vis Date: 2007-02-02 Impact factor: 2.367

9. A biomedically enriched collection of 7000 human ORF clones.

Authors: Andreas Rolfs; Yanhui Hu; Lars Ebert; Dietmar Hoffmann; Dongmei Zuo; Niro Ramachandran; Jacob Raphael; Fontina Kelley; Seamus McCarron; Daniel A Jepson; Binghua Shen; Munira M A Baqui; Joseph Pearlberg; Elena Taycher; Craig DeLoughery; Andreas Hoerlein; Bernhard Korn; Joshua LaBaer
Journal: PLoS One Date: 2008-01-30 Impact factor: 3.240

Proteomic analysis of the hyaloid vascular system regression during ocular development.

1. Role of INK4a locus in normal eye development and cataract genesis.

2. Kininostatin associates with membrane rafts and inhibits alpha(v)beta3 integrin activation in human umbilical vein endothelial cells.

3. Kininogen binding to the surfaces of macrophages.

4. PWWP module of human hepatoma-derived growth factor forms a domain-swapped dimer with much higher affinity for heparin.

Review 5. Survival factors, intracellular signal transduction, and the activation of endonucleases in apoptosis.

6. The inhibition of tube formation in a collagen-fibrinogen, three-dimensional gel by cleaved kininogen (HKa) and HK domain 5 (D5) is dependent on Src family kinases.

7. Proteomic differentiation between murine retinal and brain-derived progenitor cells.

8. Development of a microarray chip for gene expression in rabbit ocular research.

9. A biomedically enriched collection of 7000 human ORF clones.

10. Differential protein expression in tree shrew sclera during development of lens-induced myopia and recovery.

1. Semaphorin 7A promotes angiogenesis in an experimental corneal neovascularization model.

2. Proteomic Analysis of Embryonic and Young Human Vitreous.

Review 3. Novel aspects of corneal angiogenic and lymphangiogenic privilege.

4. Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye.