Rapid growing fibroadenoma in an adolescent.

INTRODUCTION: We report a case of rapidly growing fibroadenoma. PATIENT: A 13-year-old girl consulted the outpatient clinic regarding a left breast mass. The mass was diagnosed as fibroadenoma by clinical examinations, and the patient was carefully monitored. The mass enlarged rapidly with each menses and showed a 50% increase in volume four months later. Lumpectomy was performed. The tumor was histologically diagnosed as fibroadenoma organized type and many glandular epithelial cells had positive immunohistochemical staining for anti-estrogen receptor antibody in the nuclei.
CONCLUSION: The estrogen sensitivity of the tumor could account for the rapid growth.