| Literature DB >> 18840355 |
Alfred J Meijer1, Patrice Codogno.
Abstract
Autophagy is inhibited by the insulin-amino acid-mTOR signaling pathway. Two papers in this issue of Cell Metabolism (Ebato et al., 2008; Jung et al., 2008) provide evidence that basal autophagy is necessary to maintain the architecture and function of pancreatic beta cells and that its induction in diabetic mice protects beta cells against damage by oxidative stress.Entities:
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Year: 2008 PMID: 18840355 DOI: 10.1016/j.cmet.2008.09.001
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287