| Literature DB >> 18839963 |
Andrew Martins1, Mark Lautens.
Abstract
The discovery of a novel arylpalladium(II) reduction enables the synthesis of diarylmethanes via reductive benzylation. Benzyl chlorides were found to be the major source of hydride, acting as an alkylating agent and an aprotic surrogate for benzyl alcohol. This represents the first example of an arylpalladium(II) reduction mediated by a benzyl halide.Entities:
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Year: 2008 PMID： 18839963 DOI： 10.1021/ol802185x
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005