| Literature DB >> 18838582 |
A Waléria-Aleixo1, A N Martins, M B Arruda, R M Brindeiro, R M Da-Silva, F F Nobre, D B Greco, A Tanuri.
Abstract
The major human immunodeficiency virus type 1 subtype circulating in Brazil is B, followed by F and C. We have genotyped 882 samples from Brazilian patients for whom highly active antiretroviral therapy failed, and we found subtype B and the unique recombinant B/F1 forms circulating. Due to codon usage variation, there is a significantly lower incidence of the substitutions L210W, Q151M, and F116Y in subtype F1 isolates than in the subtype B counterparts.Entities:
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Year: 2008 PMID: 18838582 PMCID: PMC2592894 DOI: 10.1128/AAC.00820-08
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191