Literature DB >> 1883798

Quantitative production of prostaglandin E2 and its metabolites by human fetal membranes.

H Khan1, M H Sullivan, R Helmig, C K Roseblade, N Uldbjerg, M G Elder.   

Abstract

Cultured amnion, choriodecidua and intact fetal membrane produced similar quantities of prostaglandin E2 (PGE2) (1-5 ng/ml). Choriodecidua and intact fetal membrane also produced very high levels of PGE2 metabolites (100-1000 ng/ml). The total production of PGE (PGE2 + PGE2 metabolites) was similar in intact fetal membrane and in choriodecidua, suggesting that the amnion, although a source of PGE2, contributes little to the overall PGE production by fetal membranes.

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Year:  1991        PMID: 1883798     DOI: 10.1111/j.1471-0528.1991.tb13461.x

Source DB:  PubMed          Journal:  Br J Obstet Gynaecol        ISSN: 0306-5456


  1 in total

1.  The production of interleukin-1beta from human fetal membranes is not obligatory for increased prostaglandin output.

Authors:  S A Alvi; D Rajasingam; N L Brown; M G Elder; P R Bennett; M H Sullivan
Journal:  Immunology       Date:  1999-06       Impact factor: 7.397

  1 in total

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