Literature DB >> 18836878

Dynamic cardiomyoplasty using artificial muscle.

Yasuyuki Suzuki1, Kazuyuki Daitoku, Masahito Minakawa, Kozo Fukui, Ikuo Fukuda.   

Abstract

Dynamic cardiomyoplasty using latissimus dorsi muscle was previously used to compensate for congestive heart failure. Now, however, this method is not acceptable because the long-term result was not as expected owing to fatigue of the skeletal muscle. BioMetal fiber developed by Toki Corporation is one of the artificial muscles activated by electric current. The behavior of this fiber is similar to that of organic muscle. We made an artificial muscle like the latissimus dorsi using BioMetal fiber and tested whether we could use this new muscle as a cardiac supporting device. Testing one Biometal fiber showed the following performance: practical use maximal generative force was 30 g, exercise variation was 50%, and the standard driving current was 220 mA. We created a 4 x 12-cm tabular artificial muscle using 8 BioMetal fibers as a cardiac support device. We also made a simulation circuit composed of a 6 x 8-cm soft bag with unidirectional valves, reservoir, and connecting tube. The simulation circuit was filled with water and the soft bag was wrapped with the artificial muscle device. After powering the device electrically at 9 V with a current of 220 mA for each fiber, we measured the inside pressure and observed the movement of the artificial device. The artificial muscle contracted in 0.5 s for peak time and squeezed the soft bag. The peak pressure inside the soft bag was measured as 10 mmHg. Although further work will be needed to enhance the speed of deformability and movement simulating contraction, we conclude that artificial muscle may be potentially useful as a cardiac assistance device that can be developed for dynamic cardiomyoplasty.

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Year:  2008        PMID: 18836878     DOI: 10.1007/s10047-008-0420-9

Source DB:  PubMed          Journal:  J Artif Organs        ISSN: 1434-7229            Impact factor:   1.731


  6 in total

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Journal:  ASAIO J       Date:  1996 Sep-Oct       Impact factor: 2.872

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Review 6.  Dynamic cardiomyoplasty as a therapeutic alternative: current status.

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Journal:  Heart Fail Rev       Date:  2001-09       Impact factor: 4.214

  6 in total
  2 in total

Review 1.  Journal of Artificial Organs 2008: the year in review.

Authors:  Y Sawa; E Tatsumi; A Funakubo; T Horiuchi; K Iwasaki; A Kishida; T Masuzawa; K Matsuda; M Nishimura; T Nishimura; Y Tomizawa; T Yamaoka; H Watanabe
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Review 2.  New Insights in the Diagnosis and Treatment of Heart Failure.

Authors:  Giulio Agnetti; Massimo F Piepoli; Giuseppe Siniscalchi; Francesco Nicolini
Journal:  Biomed Res Int       Date:  2015-10-26       Impact factor: 3.411

  2 in total

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