Literature DB >> 18836666

Wound repair capability in EDS fibroblasts can be retrieved by exogenous type V collagen.

Simona Viglio1, Nicoletta Zoppi, Antonella Sangalli, Angelo Gallanti, Sergio Barlati, Monica Mottes, Marina Colombi, Maurizia Valli.   

Abstract

Impaired wound healing is a typical clinical hallmark of Ehlers-Danlos Syndrome (EDS). Mutated fibroblasts from EDS patients, which deposit an abnormal extracellular matrix, showed defective migration resulting in a marked delay in wound repair. The migratory capability remarkably improved in the presence of exogenous type V collagen.

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Year:  2008        PMID: 18836666      PMCID: PMC5849222          DOI: 10.1100/tsw.2008.131

Source DB:  PubMed          Journal:  ScientificWorldJournal        ISSN: 1537-744X


  1 in total

Review 1.  Topical Collagen-Based Biomaterials for Chronic Wounds: Rationale and Clinical Application.

Authors:  Lisa J Gould
Journal:  Adv Wound Care (New Rochelle)       Date:  2016-01-01       Impact factor: 4.730

  1 in total

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