Relief of intractable pruritus after administration of botulinum toxin A (botox): a case report.

A 55-year-old woman sought assistance for intractable pruritus of 6-year duration, affecting the right side of the forehead. She had surgery on the right frontal area for treatment of a frontal sinus condition, a few years earlier. The itch failed to respond to a variety of medical interventions, including oral antipruritic agents and local injections of anesthetic. Administration of botulinum toxin A (Allergan Inc, Irvine, CA) into the pruritic area resulted in a significant relief of pruritus in this patient.