Literature DB >> 18836016

Brucella abortus strain RB51 leucine auxotroph as an environmentally safe vaccine for plasmid maintenance and antigen overexpression.

Parthiban Rajasekaran1, Mohamed N Seleem, Andrea Contreras, Endang Purwantini, Gerhardt G Schurig, Nammalwar Sriranganathan, Stephen M Boyle.   

Abstract

To avoid potentiating the spread of an antibiotic resistance marker, a plasmid expressing a leuB gene and a heterologous antigen, green fluorescent protein (GFP), was shown to complement a leucine auxotroph of cattle vaccine strain Brucella abortus RB51, which protected CD1 mice from virulent B. abortus 2308 and elicited GFP antibodies.

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Year:  2008        PMID： 18836016      PMCID： PMC2583484          DOI： 10.1128/AEM.01511-08

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  17 in total

1.  Broad-host-range cre-lox system for antibiotic marker recycling in gram-negative bacteria.

Authors:  Christopher J Marx; Mary E Lidstrom
Journal:  Biotechniques       Date:  2002-11       Impact factor: 1.993

2.  Improved expression vector for Brucella species.

Authors:  Mohamed N Seleem; Ramesh Vemulapalli; Stephen M Boyle; Gerhardt G Schurig; Nammalwar Sriranganathan
Journal:  Biotechniques       Date:  2004-11       Impact factor: 1.993

3.  Guidance for human somatic cell therapy and gene therapy. March 1998. Center for Biologics Evaluation and Research, Food and Drug Administration.

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Journal:  Hum Gene Ther       Date:  1998-07-01       Impact factor: 5.695

4.  Transformation of Brucella species with suicide and broad host-range plasmids.

Authors:  J R McQuiston; G G Schurig; N Sriranganathan; S M Boyle
Journal:  Methods Mol Biol       Date:  1995

5.  Leucine auxotrophy restricts growth of Mycobacterium bovis BCG in macrophages.

Authors:  F C Bange; A M Brown; W R Jacobs
Journal:  Infect Immun       Date:  1996-05       Impact factor: 3.441

6.  Listeria monocytogenes-based antibiotic resistance gene-free antigen delivery system applicable to other bacterial vectors and DNA vaccines.

Authors:  Thorsten Verch; Zhen-Kun Pan; Yvonne Paterson
Journal:  Infect Immun       Date:  2004-11       Impact factor: 3.441

7.  Brucella abortus strain RB51 as a vector for heterologous protein expression and induction of specific Th1 type immune responses.

Authors:  R Vemulapalli; Y He; S M Boyle; N Sriranganathan; G G Schurig
Journal:  Infect Immun       Date:  2000-06       Impact factor: 3.441

8.  [Influence of the mouse genotype on the sensitivity to Brucella abortus 544].

Authors:  Y Le Garrec; N Garrido-Calderon; C Pilet
Journal:  Dev Biol Stand       Date:  1976

9.  Minimal requirements for growth of Brucella suis and other Brucella species.

Authors:  M Plommet
Journal:  Zentralbl Bakteriol       Date:  1991-10

10.  Cloning of genes for proline and leucine biosynthesis from Brucella abortus by functional complementation in Escherichia coli.

Authors:  R C Essenberg; Y K Sharma
Journal:  J Gen Microbiol       Date:  1993-01
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  6 in total

1.  Peptide nucleic acids inhibit growth of Brucella suis in pure culture and in infected murine macrophages.

Authors:  Parthiban Rajasekaran; Jeffry C Alexander; Mohamed N Seleem; Neeta Jain; Nammalwar Sriranganathan; Alice R Wattam; João C Setubal; Stephen M Boyle
Journal:  Int J Antimicrob Agents       Date:  2013-01-08       Impact factor: 5.283

Review 2.  Recent advances in Brucella abortus vaccines.

Authors:  Elaine M S Dorneles; Nammalwar Sriranganathan; Andrey P Lage
Journal:  Vet Res       Date:  2015-07-08       Impact factor: 3.683

3.  Development of attenuated live vaccine candidates against swine brucellosis in a non-zoonotic B. suis biovar 2 background.

Authors:  Beatriz Aragón-Aranda; María Jesús de Miguel; Leticia Lázaro-Antón; Miriam Salvador-Bescós; Amaia Zúñiga-Ripa; Ignacio Moriyón; Maite Iriarte; Pilar M Muñoz; Raquel Conde-Álvarez
Journal:  Vet Res       Date:  2020-07-23       Impact factor: 3.683

Review 4.  Auxotrophy to Xeno-DNA: an exploration of combinatorial mechanisms for a high-fidelity biosafety system for synthetic biology applications.

Authors:  Christopher M Whitford; Saskia Dymek; Denise Kerkhoff; Camilla März; Olga Schmidt; Maximilian Edich; Julian Droste; Boas Pucker; Christian Rückert; Jörn Kalinowski
Journal:  J Biol Eng       Date:  2018-08-14       Impact factor: 4.355

5.  Brucella abortus RB51 ΔleuB expressing Salmonella FliC conjugated gonadotropins reduces mouse fetal numbers: A possible feral swine brucellosis immunocontraceptive vaccine.

Authors:  Steven G Waldrop; Garrett P Smith; Stephen M Boyle; Nammalwar Sriranganathan
Journal:  Heliyon       Date:  2021-02-02

6.  Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates.

Authors:  Thomas E Todd; Omar Tibi; Yu Lin; Samantha Sayers; Denise N Bronner; Zuoshuang Xiang; Yongqun He
Journal:  BMC Bioinformatics       Date:  2013-04-17       Impact factor: 3.169
  6 in total

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