Literature DB >> 1883480

Anti-acetylcholine receptor antibodies decrease after thymectomy in patients with myasthenia gravis. Clinical correlations.

J B Kuks1, H J Oosterhuis, P C Limburg, T H The.   

Abstract

Clinical course and changes in serum levels of antibodies to the acetylcholine receptor (a-AChR) were followed in 82 patients with myasthenia gravis during a period of 1-8 years after thymectomy. Decrease in a-AChR immediately after thymectomy was influenced by changes in a total IgG. Immunosuppressive medication affected serum a-AChR at all points of time. In a subgroup of 41 patients without thymoma who had no immunosuppressive drugs, there was a steady decrease in a-AChR concomitant with clinical improvement from 6 weeks after thymectomy.

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Year:  1991        PMID： 1883480     DOI： 10.1016/0896-8411(91)90018-8

Source DB:  PubMed          Journal:  J Autoimmun        ISSN： 0896-8411            Impact factor:   7.094


  13 in total

1.  Microarrays reveal distinct gene signatures in the thymus of seropositive and seronegative myasthenia gravis patients and the role of CC chemokine ligand 21 in thymic hyperplasia.

Authors:  Rozen Le Panse; Géraldine Cizeron-Clairac; Jacky Bismuth; Sonia Berrih-Aknin
Journal:  J Immunol       Date:  2006-12-01       Impact factor: 5.422

2.  Antibodies to acetylcholine receptors in myasthenia gravis. In vitro synthesis by peripheral blood lymphocytes before and after thymectomy.

Authors:  J B Kuks; P C Limburg; H J Oosterhuis; T H The
Journal:  Clin Exp Immunol       Date:  1992-02       Impact factor: 4.330

Review 3.  Myasthenia gravis: an autoimmune response against the acetylcholine receptor.

Authors:  Y M Graus; M H De Baets
Journal:  Immunol Res       Date:  1993       Impact factor: 2.829

Review 4.  Myasthenia gravis as a prototype autoimmune receptor disease.

Authors:  A C Hoedemaekers; P J van Breda Vriesman; M H De Baets
Journal:  Immunol Res       Date:  1997       Impact factor: 2.829

Review 5.  Mechanisms of Autoantibody-Induced Pathology.

Authors:  Ralf J Ludwig; Karen Vanhoorelbeke; Frank Leypoldt; Ziya Kaya; Katja Bieber; Sandra M McLachlan; Lars Komorowski; Jie Luo; Otavio Cabral-Marques; Christoph M Hammers; Jon M Lindstrom; Peter Lamprecht; Andrea Fischer; Gabriela Riemekasten; Claudia Tersteeg; Peter Sondermann; Basil Rapoport; Klaus-Peter Wandinger; Christian Probst; Asmaa El Beidaq; Enno Schmidt; Alan Verkman; Rudolf A Manz; Falk Nimmerjahn
Journal:  Front Immunol       Date:  2017-05-31       Impact factor: 7.561

Review 6.  Vaccines against myasthenia gravis.

Authors:  Sonia Berrih-Aknin; Sara Fuchs; Miriam C Souroujon
Journal:  Expert Opin Biol Ther       Date:  2005-07       Impact factor: 4.388

7.  Visualization of the thymus by substance P receptor scintigraphy in man.

Authors:  P M van Hagen; W A Breeman; J C Reubi; P T Postema; P J van den Anker-Lugtenburg; D J Kwekkeboom; J Laissue; B Waser; S W Lamberts; T J Visser; E P Krenning
Journal:  Eur J Nucl Med       Date:  1996-11

Review 8.  Review on Toll-Like Receptor Activation in Myasthenia Gravis: Application to the Development of New Experimental Models.

Authors:  Marieke Robinet; Solène Maillard; Mélanie A Cron; Sonia Berrih-Aknin; Rozen Le Panse
Journal:  Clin Rev Allergy Immunol       Date:  2017-02       Impact factor: 8.667

9.  An acetylcholine receptor alpha subunit promoter confers intrathymic expression in transgenic mice. Implications for tolerance of a transgenic self-antigen and for autoreactivity in myasthenia gravis.

Authors:  A M Salmon; C Bruand; A Cardona; J P Changeux; S Berrih-Aknin
Journal:  J Clin Invest       Date:  1998-06-01       Impact factor: 14.808

Review 10.  Unraveling the role of ectopic thymic tissue in patients undergoing thymectomy for myasthenia gravis.

Authors:  Feng Li; Ya Tao; Gero Bauer; Aron Elsner; Zhongmin Li; Marc Swierzy; Julianna Englisch; Andreas Meisel; Mahmoud Ismail; Jens-C Rückert
Journal:  J Thorac Dis       Date:  2019-09       Impact factor: 2.895
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