Literature DB >> 18833549

Molecular basis for beta-glucosidase inhibition by ring-modified calystegine analogues.

Matilde Aguilar1, Tracey M Gloster, M Isabel García-Moreno, Carmen Ortiz Mellet, Gideon J Davies, Amadeu Llebaria, Josefina Casas, Meritxell Egido-Gabás, José M García Fernandez.   

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Year:  2008        PMID： 18833549     DOI： 10.1002/cbic.200800451

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  11 in total

1.  Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase.

Authors:  Samarjit Patnaik; Wei Zheng; Jae H Choi; Omid Motabar; Noel Southall; Wendy Westbroek; Wendy A Lea; Arash Velayati; Ehud Goldin; Ellen Sidransky; William Leister; Juan J Marugan
Journal:  J Med Chem       Date:  2012-06-08       Impact factor: 7.446

2.  The myo-1,2-Diaminocyclitol Scaffold Defines Potent Glucocerebrosidase Activators and Promising Pharmacological Chaperones for Gaucher Disease.

Authors:  Ana Trapero; Amadeu Llebaria
Journal:  ACS Med Chem Lett       Date:  2011-05-18       Impact factor: 4.345

3.  sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease.

Authors:  Manuel González-Cuesta; Irene Herrera-González; M Isabel García-Moreno; Roger A Ashmus; David J Vocadlo; José M García Fernández; Eiji Nanba; Katsumi Higaki; Carmen Ortiz Mellet
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.756

4.  Metabolomics-guided discovery of cytochrome P450s involved in pseudotropine-dependent biosynthesis of modified tropane alkaloids.

Authors:  Radin Sadre; Thilani M Anthony; Josh M Grabar; Matthew A Bedewitz; A Daniel Jones; Cornelius S Barry
Journal:  Nat Commun       Date:  2022-07-02       Impact factor: 17.694

Review 5.  Tetrazoles via Multicomponent Reactions.

Authors:  Constantinos G Neochoritis; Ting Zhao; Alexander Dömling
Journal:  Chem Rev       Date:  2019-02-01       Impact factor: 60.622

Review 6.  Glycosidase inhibition: assessing mimicry of the transition state.

Authors:  Tracey M Gloster; Gideon J Davies
Journal:  Org Biomol Chem       Date:  2009-11-05       Impact factor: 3.876

7.  Structural basis of pharmacological chaperoning for human β-galactosidase.

Authors:  Hironori Suzuki; Umeharu Ohto; Katsumi Higaki; Teresa Mena-Barragán; Matilde Aguilar-Moncayo; Carmen Ortiz Mellet; Eiji Nanba; Jose M Garcia Fernandez; Yoshiyuki Suzuki; Toshiyuki Shimizu
Journal:  J Biol Chem       Date:  2014-04-15       Impact factor: 5.157

8.  Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease.

Authors:  Mario de la Mata; David Cotán; Manuel Oropesa-Ávila; Juan Garrido-Maraver; Mario D Cordero; Marina Villanueva Paz; Ana Delgado Pavón; Elizabet Alcocer-Gómez; Isabel de Lavera; Patricia Ybot-González; Ana Paula Zaderenko; Carmen Ortiz Mellet; José M García Fernández; José A Sánchez-Alcázar
Journal:  Sci Rep       Date:  2015-06-05       Impact factor: 4.379

9.  Probing the Inhibitor versus Chaperone Properties of sp²-Iminosugars towards Human β-Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease.

Authors:  Teresa Mena-Barragán; M Isabel García-Moreno; Alen Sevšek; Tetsuya Okazaki; Eiji Nanba; Katsumi Higaki; Nathaniel I Martin; Roland J Pieters; José M García Fernández; Carmen Ortiz Mellet
Journal:  Molecules       Date:  2018-04-17       Impact factor: 4.411

Review 10.  Tuning protein folding in lysosomal storage diseases: the chemistry behind pharmacological chaperones.

Authors:  David M Pereira; Patrícia Valentão; Paula B Andrade
Journal:  Chem Sci       Date:  2018-01-10       Impact factor: 9.825
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