OBJECTIVE: This study examined the rate and predictors of major depression six months after outpatient mental health admission. METHODS: Assessments were conducted at admission and three and six months later among 166 participants. Antidepressant treatment adequacy and depression outcomes were assessed at follow-ups. RESULTS: Predictors of major depression at six months included nonremission status at three months (odds ratio [OR]=3.56, p=.003), inadequacy of early pharmacotherapy (OR=2.73, p=.009), worse physical functioning measured by the 36-Item Short-Form Health Survey (OR=.975, p<.001), and being unmarried (OR=2.54, p=.031). CONCLUSIONS: The findings support the effects of baseline physical disability, marital status, early treatment adequacy, and early remission on the course of major depression. The identification of individuals who do not receive intensive pharmacotherapy or who have not recovered by three months may provide opportunities for interventions to optimize six-month outcomes and to prevent the development of a persistent depression.
OBJECTIVE: This study examined the rate and predictors of major depression six months after outpatient mental health admission. METHODS: Assessments were conducted at admission and three and six months later among 166 participants. Antidepressant treatment adequacy and depression outcomes were assessed at follow-ups. RESULTS: Predictors of major depression at six months included nonremission status at three months (odds ratio [OR]=3.56, p=.003), inadequacy of early pharmacotherapy (OR=2.73, p=.009), worse physical functioning measured by the 36-Item Short-Form Health Survey (OR=.975, p<.001), and being unmarried (OR=2.54, p=.031). CONCLUSIONS: The findings support the effects of baseline physical disability, marital status, early treatment adequacy, and early remission on the course of major depression. The identification of individuals who do not receive intensive pharmacotherapy or who have not recovered by three months may provide opportunities for interventions to optimize six-month outcomes and to prevent the development of a persistent depression.
Authors: James H Kocsis; Alan J Gelenberg; Barbara Rothbaum; Daniel N Klein; Madhukar H Trivedi; Rachel Manber; Martin B Keller; Robert Howland; Michael E Thase Journal: J Affect Disord Date: 2008-02-12 Impact factor: 4.839
Authors: Jeffrey B Weilburg; Kathleen M O'Leary; James B Meigs; John Hennen; Randall S Stafford Journal: Psychiatr Serv Date: 2003-09 Impact factor: 3.084
Authors: Barnett S Meyers; Jo Anne Sirey; Martha Bruce; Mimi Hamilton; Patrick Raue; Steven J Friedman; Cynthia Rickey; Tatsu Kakuma; Melissa K Carroll; Dimitris Kiosses; George Alexopoulos Journal: Arch Gen Psychiatry Date: 2002-08
Authors: Mohamed S Al-Moamary; Sami A Alhaider; Abdullah A Alangari; Mohammed O Al Ghobain; Mohammed O Zeitouni; Majdy M Idrees; Abdullah F Alanazi; Adel S Al-Harbi; Abdullah A Yousef; Hassan S Alorainy; Mohamed S Al-Hajjaj Journal: Ann Thorac Med Date: 2019 Jan-Mar Impact factor: 2.219
Authors: Natalie A Cort; Stephanie A Gamble; Phillip N Smith; Linda H Chaudron; Naiji Lu; Hua He; Nancy L Talbot Journal: Depress Anxiety Date: 2012-05-08 Impact factor: 6.505
Authors: Mohamed S Al-Moamary; Sami A Alhaider; Majdy M Idrees; Mohammed O Al Ghobain; Mohammed O Zeitouni; Adel S Al-Harbi; Abdullah A Yousef; Hussain Al-Matar; Hassan S Alorainy; Mohamed S Al-Hajjaj Journal: Ann Thorac Med Date: 2016 Jan-Mar Impact factor: 2.219